C3175

Chloramphenicol-Water Soluble

powder, BioReagent, suitable for cell culture

• Synonym(s): Chloramphenicol, Chlornitromycin, Chlorocid, Chloromycetin, Cloramfenicol, D-(−)-threo-2-Dichloroacetamido-1-(4-nitrophenyl)-1,3-propanediol, D-(−)-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-β-(4-nitrophenyl)ethyl]acetamide, Chloromycetin, D-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-4-nitrophenethyl]aceta, Kloramfenikol
• NACRES: NA.76

Properties

• product line: BioReagent
• Quality Level: 200
• form: powder
• technique(s): cell culture | mammalian: suitable
• solubility: H₂O: 50-500 mg/mL (stock solution); PBS: 50-500 mg/mL (stock solution); other salt solutions: not recommended
• antibiotic activity spectrum: Gram-negative bacteria; Gram-positive bacteria; mycobacteria; mycoplasma
• Mode of action: protein synthesis | interferes

Description

Application

Chloramphenicol-Water Soluble has been used:

• as a supplement in Luria-Bertani (LB) medium to culture Escherichia coli
• as a supplement in LB agar to culture Citrobacter rodentium
• to culture Toxoplasma gondii

Packaging

100 mg in glass bottle

Package size based on chloramphenicol

Biochem/physiol Actions

Chloramphenicol is a natural product found in Streptomyces venezuelae. It shows a broad range of antibiotic activity against Gram-negative and Gram-positive bacteria by binding to the peptidyl transferase loop of the ribosomal RNA to block the peptide bond formation.

Other Notes

Formulated to contain approx. 100 mg chloramphenicol per gram of powder; balance 2-hydroxypropyl-β-cyclodextrin.

Keep container tightly closed in a dry and well-ventilated place. Light sensitive. Keep in a dry place.

Safety Information

• Pictograms: GHS05,GHS08
• Signal Word: Danger
• Hazard Statements: H318 - H351 - H361fd
• Precautionary Statements: P202 - P280 - P305 + P351 + P338 - P308 + P313 - P405 - P501
• Hazard Classifications: Carc. 2 - Eye Dam. 1 - Repr. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves