All Photos(4)

C7263

Sigma-Aldrich

Calcium phosphate dibasic

98.0-105.0%

Synonym(s):
Calcium hydrogen phosphate
Linear Formula:
CaHPO4
CAS Number:
Molecular Weight:
136.06
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

Quality Level

assay

98.0-105.0%

form

powder

SMILES string

[Ca++].OP([O-])([O-])=O

InChI

1S/Ca.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+2;/p-2

InChI key

FUFJGUQYACFECW-UHFFFAOYSA-L

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Application

Calcium phosphate dibasic has been used:
  • to prepare high temperature stoichiometric sintered hydroxyapatite (sin-HA)
  • as a component of calcium phosphate cement (CPC) to prepare bioartificial pancreas (BAP)
  • to produce calcium pyrophosphate (Ca2P2O7) for the preparation of α-tricalcium phosphates (α-TCP)

Packaging

2.5 kg in poly bottle
100, 500 g in poly bottle

Biochem/physiol Actions

Calcium phosphate dibasic is an anhydrate used to dilute tablets and capsules. It is widely used as an excipient for its compressibility, amenability, and brittle fracture propensity.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Certificate of Origin

Anna Diez-Escudero et al.
Tissue engineering. Part C, Methods, 23(2), 118-124 (2017-01-14)
This article presents the application of dual focused ion beam/scanning electron microscopy (FIB-SEM) imaging for preclinical testing of calcium phosphates with osteoclast precursor cells and how this high-resolution imaging technique is able to reveal microstructural changes at a level of
Aditya M Kaushal et al.
Journal of pharmaceutical sciences, 100(4), 1456-1466 (2011-04-01)
Dibasic calcium phosphate occurs as an anhydrate (DCPA; CaHPO₄) and as a dihydrate (DCPD; CaHPO₄•2H₂O). Our objective was to investigate the unusual behavior of these phases. Dibasic calcium phosphate dihydrate was dehydrated in a (i) differential scanning calorimeter (DSC) in
Kai-Chiang Yang et al.
Transplantation, 90(6), 604-611 (2010-01-06)
Fibrous tissue outgrowth and hypoxia are the major restrictions for the application of bioartificial pancreas (BAP). Accordingly, the intramedullary cavity is proposed as an implant site, and a BAP constructed of calcium phosphate cement chamber was implanted. Mouse insulinoma cells
C L Camiré et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 79(1), 159-165 (2006-04-15)
Alpha phase tricalcium phosphates (alpha-TCP) were produced using a solid-state reaction method and milled for various periods of time. The resulting four materials were alpha-TCPs, ranging in crystalline content. Powders were exposed to X-ray diffraction for material identification as well
Tae-Woo Kim et al.
Tissue engineering and regenerative medicine, 17(5), 607-624 (2020-08-18)
The delivery of growth factors using a carrier system presents a promising and innovative tool in tissue engineering and dentistry today. Two of the foremost bioactive factors, bone morphogenetic protein-2 and vascular endothelial growth factor (VEGF), are widely applied using

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