L1376

Linoleic acid

≥99%

• Synonym(s): Telfairic acid, 9-cis,12-cis-Linoleic acid, cis-9,cis-12-Octadecadienoic acid
• Linear Formula: CH₃(CH₂)₄CH=CHCH₂CH=CH(CH₂)₇CO₂H
• CAS Number: 60-33-3
• Molecular Weight: 280.45
• Beilstein: 1727101
• EC Number: 200-470-9
• MDL number: MFCD00064241
• PubChem Substance ID: 24896279

Properties

• Quality Level: 200
• biological source: plant oil (safflower)
• assay: ≥99%
• form: liquid
• refractive index: n20/D 1.466 (lit.)
• bp: 229-230 °C/16 mmHg (lit.)
• mp: −5 °C (lit.)
• density: 0.902 g/mL at 25 °C (lit.)
• functional group: carboxylic acid
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: OC(CCCCCCC/C=C\C/C=C\CCCCC)=O
• InChI: 1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)/b7-6-,10-9-
• InChI key: OYHQOLUKZRVURQ-HZJYTTRNSA-N
• Gene Information: human ... SOAT1(6646) , SOAT2(8435)

Description

Packaging

1, 5, 10, 25 g in ampule

10, 500 mg in ampule

Biochem/physiol Actions

Linoleic acid is an n-6 polyunsaturated essential fatty acid (PUFA) used as a precursor of arachidonic acid (AA) and various prostaglandins. Linoleic acid may be used to improve the delivery and efficacy of anticancer drugs and in cancer protection.

Linoleic acid increases cell proliferation and gene expression of PPARα and its target genes such as acyl-CoA oxidase in primary duck hepatocytes .

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves