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Sodium dodecyl sulfate

BioReagent, suitable for electrophoresis, for molecular biology, ≥98.5% (GC)

Lauryl sulfate sodium salt, Sodium lauryl sulfate, Dodecyl sulfate sodium salt, SDS, Dodecyl sodium sulfate
Linear Formula:
CAS Number:
Molecular Weight:
EC Number:
MDL number:
PubChem Substance ID:

Quality Level


for molecular biology



product line



≥98.5% (GC)

mol wt

micellar 18,000

aggregation number



electrophoresis: suitable


7-10 mM (20-25°C)


204-207 °C (lit.)

transition temp

cloud point >100 °C


water: soluble

anion traces

chloride (Cl-): ≤500 ppm
phosphate (PO43-): ≤10 ppm

cation traces

heavy metals (as Pb): ≤10 ppm


≤0.1 at 260 at 3%
≤0.1 at 280 at 3%




suitable for electrophoresis

foreign activity

DNase, RNase, none detected

SMILES string




InChI key


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General description

Sodium dodecyl sulfate (SDS) is an anionic detergent suitable to denature proteins. It has a long-chain aliphatic group with negatively charged sulfate attached. This makes SDS an amphipathic detergent.


Sodium dodecyl sulfate has been used:
  • in chromatin immunoprecipitation
  • in SDS-polyacrylamide gel electrophoresis (SDS-PAGE)
  • as a component of radioimmunoprecipitation assay buffer for immunoblotting
Used to solubilize and denature proteins for denaturing-PAGE. Most proteins bind SDS in a ratio of 1.4 g SDS per gram of protein. The charges intrinsic to the protein become insignificant compared to the overall negative charge provided by the bound SDS. The charge to mass ratio is essentially the same for each protein and will migrate in the gel based only on their size.
Anionic detergent


25, 100, 500 g in poly bottle
1 kg in poly bottle

Analysis Note

Tested for use in denatured polyacrylamide gel electrophoresis.

Signal Word


Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Sol. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

4.1B - Flammable solid hazardous materials



Flash Point(F)

338.0 °F

Flash Point(C)

170 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Kazuya Ishikawa et al.
Nature communications, 5, 5430-5430 (2014-11-13)
Pathogen effector proteins are delivered to host cells to suppress plant immunity. However, the mechanisms by which effector proteins function are largely unknown. Here we show that expression of XopP(Xoo), an effector of rice pathogen Xanthomonas oryzae pv. oryzae, in
Shane Stegeman et al.
Endocrine-related cancer, 22(2), 265-276 (2015-02-12)
The oncogene MDM4, also known as MDMX or HDMX, contributes to cancer susceptibility and progression through its capacity to negatively regulate a range of genes with tumour-suppressive functions. As part of a recent genome-wide association study it was determined that
S Bavamian et al.
Molecular psychiatry, 20(5), 573-584 (2015-01-28)
Bipolar disorder (BD) is a heritable neuropsychiatric disorder with largely unknown pathogenesis. Given their prominent role in brain function and disease, we hypothesized that microRNAs (miRNAs) might be of importance for BD. Here we show that levels of miR-34a, which
Tadayoshi Hayata et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 30(2), 318-329 (2014-08-27)
Transforming growth factor (TGF)-β signaling plays critical roles during skeletal development and its excessive signaling causes genetic diseases of connective tissues including Marfan syndrome and acromelic dysplasia. However, the mechanisms underlying prevention of excessive TGF-β signaling in skeletogenesis remain unclear.
Satoshi Fukuyama et al.
Nature communications, 6, 6600-6600 (2015-03-26)
Seasonal influenza A viruses cause annual epidemics of respiratory disease; highly pathogenic avian H5N1 and the recently emerged H7N9 viruses cause severe infections in humans, often with fatal outcomes. Although numerous studies have addressed the pathogenicity of influenza viruses, influenza


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