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L4395

Sigma-Aldrich

Liposome Kit: Lipid mixtures for the preparation of liposomes

lyophilized powder

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Synonym(s):
cholesterol, L-α-phosphatidylcholine and stearylamine kit
EC Number:
UNSPSC Code:
12352211
NACRES:
NA.25

biological source

egg yolk

Quality Level

form

lyophilized powder

composition

Cholesterol, 9 μmol/package
L-α-Phosphatidylcholine (egg yolk), 63 μmol/package
Stearylamine, 18 μmol/package

functional group

carboxylic acid

shipped in

ambient

storage temp.

−20°C

Application

Liposome Kit has been used for the preparation of liposomes.

Biochem/physiol Actions

Liposome Kit: Lipid mixtures for the preparation of liposomes contains cholesterol; L-α-phosphatidylcholine and stearylamine. Liposome kit may be used to prepare cationic (positively charge) liposomes for incorporation of materials into cells.
Liposomes can be used for different applications such as drug delivery, diagnostics, membrane models, adjuvants for vaccination and others. This lipid mixture can be used to encapsulate a broad spectrum of hydrophilic and amphipathic molecules of low, medium, and high molecular weight (including peptides, proteins, and oligo- and polynucleotides).

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Pictograms

CorrosionEnvironment

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Rui Xu et al.
Analytical chemistry, 88(21), 10390-10394 (2016-11-02)
Chemical analysis of small extracellular vesicles (sEVs) circulating in body fluids holds potentials in noninvasive diagnosis of diseases and evaluation of therapeutic treatments. However, quantification of sEVs remains a challenge due to lacking of cost-effective analytical protocols. Herein we report
Quantification of small extracellular vesicles by size exclusion chromatography with fluorescence detection
Xu R, et al.
Analytical Chemistry, 88(21), 10390-10394 (2016)
Abd Kakhar Umar et al.
Molecules (Basel, Switzerland), 26(17) (2021-09-11)
Human epidermal growth factor (hEGF) has been known to have excellent wound-healing activity. However, direct application to the wound area can lead to low hEGF bioavailability due to protease enzymes or endocytosis. The use of liposomes as coatings and carriers
Abstracts of the Congress of the European Association of Nuclear Medicine. 25-29 August 2001, Napoli, Italy.
European journal of nuclear medicine, 28(8), 961-1298 (2001-09-06)
Preparation and pharmacodynamic evaluation of liposomes of indomethacin.
Srinath P, Vyas SP, Diwan PV.
Drug Devel. Ind. Pharm., 26, 313-321 (2000)

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