L8134

Linoleic acid sodium salt

≥98% (GC)

• Synonym(s): cis-9,cis-12-Octadecadienoic acid sodium salt
• Linear Formula: C₁₈H₃₁O₂Na
• CAS Number: 822-17-3
• Molecular Weight: 302.43
• EC Number: 212-491-0
• MDL number: MFCD00063202
• PubChem Substance ID: 24896493
• NACRES: NA.25

Properties

• biological source: plant oil (safflower)
• Quality Level: 200
• assay: ≥98% (GC)
• form: powder
• functional group: carboxylic acid
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: [Na+].CCCCC\C=C/C\C=C/CCCCCCCC([O-])=O
• InChI: 1S/C18H32O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20);/q;+1/p-1/b7-6-,10-9-;
• InChI key: WYPBVHPKMJYUEO-NBTZWHCOSA-M

Description

General description

Linoleic acid, a common polyunsaturated fatty acid (PUFA) found in plant oils, is the shortest chain n-6 fatty acid. It may also be present in commercial oils, like cottonseed, corn, soybean, safflower, and sunflower.

Application

Linoleic acid sodium salt has been used:

• in the β-carotene-linoleic acid assay
• as a component in basal medium to treat peripheral blood mononuclear cells (PBMCs)
• in Dulbecco′s modified Eagle′s medium (DMEM)/F-12 HEPES (4-(2-hydroxyethyl) piperazine-1-ethanesulfonic acid) to incubate human trophoblast-derived choriocarcinoma cells (BeWo) and study its effects on adherens junctions (AJ) marker level, cell layer permeability, and intracellular lipid accumulation

Packaging

100, 500 mg in serum bottle

1, 5 g in serum bottle

Biochem/physiol Actions

Linoleic acid, as a component of acylglycosyl ceramides, plays a physiological role in maintaining the water permeability barrier of the skin. The deficiency of linoleic acid may cause poor growth or development, scaly dermatitis, and an impaired immune response in infants. It is used in cosmetic and personal care products. Linoleic acid is mainly used as emollients or moisturizers for skin, nails, and hair.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315
• Hazard Classifications: Skin Irrit. 2
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves