L8384

Linoleic Acid-Albumin from bovine serum albumin

γ-irradiated, lyophilized powder, BioReagent, suitable for cell culture

• NACRES: NA.75

Properties

• biological source: bovine plasma
• Quality Level: 200
• description: Contains 1.1-2.3 moles linoleic acid per mole BSA
• sterility: γ-irradiated
• product line: BioReagent
• form: lyophilized powder
• technique(s): cell culture | mammalian: suitable
• impurities: ≤50 EU/mg endotoxin
• solubility: water: 10 mg/mL, clear to hazy, colorless to light yellow
• storage temp.: 2-8°C

Description

General description

Linoleic acid is an essential and highly consumed polyunsaturated fatty acid (PUFA). Albumin is a globular protein. Bovine serum albumin (BSA) is composed of a single polypeptide chain and cross-linked cysteine disulfide bridges. BSA is heart-shaped and is made up of three homologous domains I-III and each domain has two subdomains A and B.

Application

Linoleic Acid-Albumin from bovine serum albumin has been used: in cell culture and to study its effects on the human colonic adenocarcinoma cell line. It has also been used in the in vitro culture (IVC) of cow embryos/zygotes. The binding of linoleic acid to BSA improves its stability and solubility in culture media.

Biochem/physiol Actions

Linoleic acid plays a role in maintaining the transdermal water barrier in epidermis. Serum albumin constitutes about 52-62% of the total water-soluble fraction proteins in the blood plasma.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable