Poly-L-ornithine is a positively charged synthetic amino acid polymer.
Poly-L-ornithine has been used successfully for the attachement and study of neural cell differentiation and outgrowth. Recommended as a cell culture substratum when using 0.5 ml of a 0.1 mg/ml solution to coat 25 cm2.
Poly-L-ornithine solution has been used in the induction of differentiation.
Poly-L-ornithine helps to improve the penetration of substances into cells. It can induce the uptake of DNA.