SML2157

Homoplantaginin

≥98% (HPLC)

• Synonym(s): 4′,5,7-Trihydroxy 6-methoxyflavone 7-glucoside, 6-Methoxyapigenin 7-O-β-D-glucoside, 6-Methoxyapigenin 7-O-glucoside, 6-Methylscutellarein 7-glucoside, 7-(β-D-Glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one, Dinatin 7-glucoside, Hispidulin 7-β-glucoside, Hispiduloside, Salvitin 7-glucoside, Scutellarein 6-methyl ether 7-glucoside
• Empirical Formula (Hill Notation): C₂₂H₂₂O₁₁
• CAS Number: 17680-84-1
• Molecular Weight: 462.40
• MDL number: MFCD04039835
• NACRES: NA.77

Properties

• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: −20°C

Description

Packaging

5, 25 mg

Biochem/physiol Actions

Homoplantaginin is and anti-inflammatory and antioxidant flavonoid isolated from medical herb Salvia plebeian (Sage weed) that improves hepatic injury, hyperlipidemia, and hyperglycemia. Homoplantaginin ameliorates endothelial insulin resistance by inhibiting inflammation and modulating cell signalling via the IKKβ/IRS-1/pAkt/peNOS pathway. Homoplantaginin protects endothelial cells from Palmitic acid -induced inflammation by suppression of TLR4 expression, and NLRP3 inflammasome activation.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable