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Marcos A Maioli et al.
Toxicology in vitro : an international journal published in association with BIBRA, 27(2), 570-579 (2012-11-13)
Abamectin (ABA), which belongs to the family of avermectins, is used as a parasiticide; however, ABA poisoning can impair liver function. In a previous study using isolated rat liver mitochondria, we observed that ABA inhibited the activity of adenine nucleotide
W Dermauw et al.
Insect biochemistry and molecular biology, 42(7), 455-465 (2012-04-03)
The cys-loop ligand-gated ion channel (cysLGIC) super family of Tetranychus urticae, the two-spotted spider mite, represents the largest arthropod cysLGIC super family described to date and the first characterised one within the group of chelicerates. Genome annotation, phylogenetic analysis and
J A Lasota et al.
Acta Leidensia, 59(1-2), 217-225 (1990-01-01)
The avermectins are a family of macrocyclic lactones, produced by the soil organism Streptomyces avermitilis, which were discovered in the mid-1970's as a direct result of a screening effort for natural products with anthelmintic properties. Avermectin B1 (abamectin), the major
S D George et al.
Veterinary parasitology, 188(1-2), 190-193 (2012-03-31)
Anthelmintic resistance by gastrointestinal nematodes of sheep continues to be an issue of global interest. While the recent introduction in some countries of one or two new anthelmintic classes (amino-acetonitrile derivatives [AAD] and spiroindoles [SI]) has been welcomed, it is
Juliana C Castanha Zanoli et al.
Toxicology in vitro : an international journal published in association with BIBRA, 26(1), 51-56 (2011-10-26)
Abamectin (ABA) is a macrocyclic lactone of the avermectin family used worldwide as an antiparasitic agent in farm animals and pets and as the active ingredient of insecticides and nematicides. In this study, the effects of abamectin on the bioenergetics
Md Musfiqur Rahman et al.
Environmental monitoring and assessment, 185(11), 9461-9469 (2013-06-05)
The pre-harvest residue limit (PHRL) of abamectin (abamectin B1a and B1b) in Perilla frutescens leaves grown under greenhouse conditions were investigated using high-performance liquid chromatography with a fluorescence detector. Samples were extracted with acetonitrile. The extract was purified through a
Shinawar Waseem Ali et al.
World journal of microbiology & biotechnology, 28(1), 39-45 (2012-07-19)
Burkholderia sp. GB-01 strain was used to study different factors affecting its growth for inoculum production and then evaluated for abamectin degradation in soil for optimization under various conditions. The efficiency of abamectin degradation in soil by strain GB-01 was
Xiaojie Liu et al.
Frontiers in plant science, 8, 903-903 (2017-06-15)
The high structural diversity of plant metabolites suggests that interactions among them should be common. We investigated the effects of single metabolites and combinations of plant metabolites on insect herbivores. In particular we studied the interacting effects of pyrrolizidine alkaloid
Peter R Little et al.
Veterinary parasitology, 181(2-4), 180-193 (2011-06-21)
Derquantel (DQL), a semi-synthetic member of a novel anthelmintic class, the spiroindoles, in combination with abamectin (ABA) [as the combination product STARTECT(®)] is a new entry for the treatment and control of parasites in sheep. The 19 studies reported herein
Anna Kulik et al.
Acta poloniae pharmaceutica, 68(4), 467-472 (2011-07-30)
The purpose of the study was to develop a simple, versatile HPLC method for the identification and quantification of praziquantel and ivermectin (in Equimax) or praziquantel and abamectin (in Abamitel Plus). A satisfactory separation was obtained using the Supelcosil LC-ABZ+
Rajarshi Ghosh et al.
Science (New York, N.Y.), 335(6068), 574-578 (2012-02-04)
Resistance of nematodes to anthelmintics such as avermectins has emerged as a major global health and agricultural problem, but genes conferring natural resistance to avermectins are unknown. We show that a naturally occurring four-amino-acid deletion in the ligand-binding domain of
Antonio Biondi et al.
Chemosphere, 87(7), 803-812 (2012-02-22)
The generalist predator Orius laevigatus (Fieber) (Hemiptera: Anthocoridae) is a key natural enemy of various arthropods in agricultural and natural ecosystems. Releases of this predator are frequently carried out, and it is included in the Integrated Pest Management (IPM) programs
Andréa Novelli et al.
Chemosphere, 86(1), 36-40 (2011-10-01)
Abamectin is used as an acaricide and insecticide for fruits, vegetables and ornamental plants, as well as a parasiticide for animals. One of the major problems of applying pesticides to crops is the likelihood of contaminating aquatic ecosystems by drift
Ciler Celik-Ozenci et al.
Regulatory toxicology and pharmacology : RTP, 61(3), 310-317 (2011-09-29)
Despite the known adverse effects of abamectin pesticide, little is known about its action on male fertility. To explore the effects of exposure to abamectin on male fertility and its mechanism, low (1mg/kg/day) and high dose (4 mg/kg/day) abamectin were
Determination of abamectin and azadirachtin residues in orange samples by liquid chromatography?electrospray tandem mass spectrometry.
Pozo, O. J., et al.
Journal of Chromatography A, 992.1, 133-140 (2003)
J Learmount et al.
Veterinary parasitology, 187(1-2), 244-253 (2012-01-27)
UK guidelines for the sustainable control of parasites in sheep (SCOPS) aim to delay further development of anthelmintic drug resistance. This study describes a computer model evaluation of resistance development with a novel oral formulation of derquantel-abamectin, to inform recommendations
Thomas Geurden et al.
Veterinary parasitology, 189(2-4), 308-316 (2012-05-09)
The objective of the present studies was to evaluate the efficacy of a combined formulation (Startect(®) Dual Active Oral Solution for Sheep, Pfizer Animal Health) of derquantel (DQL) and abamectin (ABA) for the treatment of: (1) sheep experimentally infected with
Maria Edna Tenório Nunes et al.
Ecotoxicology (London, England), 21(4), 1063-1071 (2012-02-03)
Obtaining ecotoxicological data on pesticides in tropical regions is imperative for performing more realistic risk analysis, and avoidance tests have been proposed as a useful, fast and cost-effective tool. Therefore, the present study aimed to evaluate the avoidance behavior of
De-Liang Gao et al.
Ying yong sheng tai xue bao = The journal of applied ecology, 22(11), 3026-3032 (2012-02-07)
By the methods of fumigation and contact assay, this paper determined the toxicity of four kinds of soil fumigants and six kinds of non-fumigants against Ditylenchus destructor. In the meantime, the bioactivity of the agents was evaluated by the corrected
Clinical safety of rapid sequential administration of moxidectin injection and oral derquantel-abamectin as a quarantine treatment for introduced sheep.
D J Bartram et al.
The Veterinary record, 172(16), 426-426 (2013-03-26)
Kang Qiao et al.
Pest management science, 68(6), 853-857 (2012-03-08)
Tomato growers in Shandong Province, China, commonly face heavy root-knot nematode infestations. Current methods of control include cadusafos and methyl bromide (MeBr), but alternative methods are required because of the high toxicity of these pesticides and the ecological risk of
Fernando A Borges et al.
Tropical animal health and production, 45(3), 723-727 (2012-10-19)
The performance of grazing cattle in tropical areas is deeply influenced by parasitism, and the increasing reports of resistance are a threat to effective nematode control. The present study aimed to evaluate the effect of avermectins on the performance of
K Parton et al.
New Zealand veterinary journal, 60(3), 194-197 (2012-02-15)
A 5-year-old entire female Huntaway from a sheep and beef farm was one of four dogs that developed clinical signs including hypersalivation, depression, blindness and ataxia after the death of another dog. A 4-year-old female Huntaway farm dog from a
Andréa Novelli et al.
Ecotoxicology and environmental safety, 75(1), 87-93 (2011-09-23)
The present study aimed to evaluate the interactions of the pesticide Vertimec(®) 18EC in aquatic ecosystems. In this respect, soil plots were contaminated with Vertimec(®) 18EC at the concentration indicated for strawberry crops (0.125L of solution m(-2)). After the contamination
Welber Daniel Zanetti Lopes et al.
Experimental parasitology, 135(1), 72-78 (2013-06-26)
The present study therefore assessed the deleterious effects of MLs (ivermectin, abamectin, doramectin and moxidectin) on the reproductive parameters of engorged Rhipicephalus (Boophilus) microplus females that naturally detached from experimentally infested cattle in two experiments. The following reproductive parameters of
Heinz Sager et al.
Parasitology research, 111(5), 2205-2207 (2012-05-12)
Drug resistance in gastrointestinal nematodes is a severe problem for sheep farmers. With the recent introduction of monepantel (Zolvix®) and of derquantel plus abamectin (Startect®) in New Zealand, two new anthelmintic classes will be available to control gastrointestinal nematodes. While
Qodratollah Sabahi et al.
Journal of insect science (Online), 11, 104-104 (2012-01-10)
The toxicity of three insecticides to Lysiphlebus fabarum (Marshall) (Hymenoptera: Braconidae: Aphidiinae), a parasitoid of Aphis fabae Scopoli (Hemiptera: Aphididae), was investigated using IOBC/wprs protocols. Abamectin 1.8 EC, imidacloprid 350 SC, and pymetrozine 25 WP were tested under laboratory conditions
Anja M Carlsson et al.
Parasitology, 139(8), 1086-1092 (2012-03-16)
In order to quantify the impact of parasites on host population dynamics, experimental manipulations that perturb the parasite-host relationship are needed but, logistically, this is difficult for wild hosts. Here, we describe the use of a delayed-release anthelmintic delivery system
Evolution. Surviving in a toxic world.
Adrian J Wolstenholme
Science (New York, N.Y.), 335(6068), 545-546 (2012-02-04)
Alice Melotti et al.
EMBO molecular medicine, 6(10), 1263-1278 (2014-08-22)
Constitutive activation of canonical WNT-TCF signaling is implicated in multiple diseases, including intestine and lung cancers, but there are no WNT-TCF antagonists in clinical use. We have performed a repositioning screen for WNT-TCF response blockers aiming to recapitulate the genetic
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