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46451

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Martin Knaus et al.
Veterinary parasitology, 202(1-2), 40-44 (2014-04-08)
The efficacy of a novel topical fipronil, (S)-methoprene, eprinomectin and praziquantel combination product (BROADLINE(®), Merial) was evaluated against adult Toxascaris leonina ascarids in experimentally infected cats in two controlled studies under an identical protocol. For each study, 30 nematode-naive, purpose-bred
Cai Wang et al.
Journal of economic entomology, 106(6), 2630-2632 (2014-02-07)
Fipronil is a widely used insecticide for termite control. Although transfer of fipronil among termite cohorts has been investigated in previous studies, no study has yet focused on the influence of termite group size (density) on horizontal transfer. In this
Béatrice B Roques et al.
Biochemical pharmacology, 86(7), 997-1039 (2013-08-22)
Fipronil is described as a thyroid disruptor in rat. Based on the hypothesis that this results from a perturbation of hepatic thyroid hormone metabolism, our goal was to investigate the pathways involved in fipronil-induced liver gene expression regulations. First, we
Martin Knaus et al.
Veterinary parasitology, 202(1-2), 34-39 (2014-04-08)
The efficacy of a novel topical combination of fipronil 8.3% (w/v), (S)-methoprene 10% (w/v), eprinomectin 0.4% (w/v), and praziquantel 8.3% (w/v) (BROADLINE(®), Merial) was evaluated against adult and larval Toxocara cati in four controlled studies. All studies included experimentally infected
Daniel A Spudeit et al.
Journal of chromatography. A, 1363, 89-95 (2014-08-30)
This work reports a comparison of HPLC separations of enantiomers with chiral stationary phases (CSPs) prepared by chemically bonding cyclofructan-6, functionalized with isopropyl carbamate groups on fully and superficially porous particles (SPPs). The chromatographic performance of the superficially porous CSP
Ling-Hui Ang et al.
Journal of economic entomology, 106(5), 2167-2176 (2013-11-15)
Extensive usage and heavy reliance on insecticides have led to the development of insecticide resistance in the German cockroach, Blattella germanica (L.). Six field-collected strains of B. germanica from Singapore were used to investigate resistance to fipronil and dieldrin. The
Stephan M Carvalho et al.
Environmental toxicology and chemistry, 32(9), 2117-2124 (2013-05-29)
The present study was intended to evaluate the responses of enzymes in the honeybee Apis mellifera after exposure to deltamethrin, fipronil, and spinosad and their use as biomarkers. After determination of the median lethal doses (LD50), honeybees were exposed at
Steffen Rehbein et al.
Veterinary parasitology, 202(1-2), 10-17 (2014-04-08)
A novel topical combination product (BROADLINE(®), Merial) composed of fipronil, (S)-methoprene, eprinomectin and praziquantel was evaluated for safety and efficacy against nematode and cestode infections in domestic cats. The study comprised a multi-centre, positive control, blinded, field study, using a
Christine F Baker et al.
Veterinary parasitology, 202(1-2), 49-53 (2014-04-08)
Cats may be infected by heartworm, Dirofilaria immitis, through mosquito bites. They can develop severe heartworm disease when infective D. immitis larvae migrate and develop into adults in the pulmonary vasculature or other tissues. As there is no curative treatment
E Tielemans et al.
Veterinary parasitology, 202(1-2), 59-63 (2014-04-08)
Five controlled, blinded and randomized studies were conducted to examine the efficacy of a single topical application of a combination of fipronil, (S)-methoprene, eprinomectin, and praziquantel (BROADLINE(®), Merial) against induced infestations with Ixodes ticks on cats. Three studies investigated the
Emily J Remnant et al.
Insect biochemistry and molecular biology, 54, 11-21 (2014-09-07)
Extensive use of older generation insecticides may result in pre-existing cross-resistance to new chemical classes acting at the same target site. Phenylpyrazole insecticides block inhibitory neurotransmission in insects via their action on ligand-gated chloride channels (LGCCs). Phenylpyrazoles are broad-spectrum insecticides
Martin Knaus et al.
Veterinary parasitology, 202(1-2), 18-25 (2014-04-08)
The efficacy of a novel topical combination formulation of fipronil, (S)-methoprene, eprinomectin and praziquantel against naturally acquired intestinal nematode and cestode infections in cats was evaluated in seven negative control, blinded studies. Cats were selected based on a pre-treatment faecal
Valerie Kvaternick et al.
Veterinary parasitology, 202(1-2), 2-9 (2014-04-08)
Four studies were conducted to determine the pharmacokinetic characteristics and in vitro metabolism of eprinomectin, a semi-synthetic avermectin, in cats. Pharmacokinetic parameters including bioavailability of eprinomectin were determined in a parallel study design comprised of one group of eight cats
Eric Tielemans et al.
Veterinary parasitology, 202(1-2), 26-29 (2014-04-08)
Although foxes are the main reservoir of Echinococcus multilocularis, it is recognized that dogs and cats also may become infected. In cats the infection and egg production rates are usually low. Nevertheless, cats are a potential source of transmission of
George Xavier et al.
Environmental monitoring and assessment, 186(9), 5429-5437 (2014-05-13)
A single laboratory UPLC-MS/MS method was developed and validated for the estimation of fipronil and its metabolites in fresh and dry chilli pepper fruits. Dissipation of fipronil on chilli fruits was studied following the application of fipronil (Jump 80 WG)
Virginia C Moser et al.
Toxicology and applied pharmacology, 282(2), 161-174 (2014-12-17)
There is increasing emphasis on the use of biomarkers of adverse outcomes in safety assessment and translational research. We evaluated serum biomarkers and targeted metabolite profiles after exposure to pesticides (permethrin, deltamethrin, imidacloprid, carbaryl, triadimefon, fipronil) with different neurotoxic actions.
Colin C D Tingle et al.
Reviews of environmental contamination and toxicology, 176, 1-66 (2002-11-22)
Fipronil is a highly effective, broad-spectrum insecticide with potential value for the control of a wide range of crop, public hygiene, amenity, and veterinary pests. It can generally be applied at low to very low dose rates to achieve effective
Sunayana Saini et al.
Environmental monitoring and assessment, 186(1), 69-75 (2013-08-01)
Fipronil belongs to phenylpyrazole class of chemical compounds. Degradation of fipronil in sandy loam soil was investigated under field conditions by applying fipronil (Regent 5 % SC) at 50 (T 1) and 100 g a.i. ha(-1) (T 2) in field. Samples were
Haihua Wu et al.
Pesticide biochemistry and physiology, 115, 9-14 (2014-10-14)
The acute toxicity of fipronil and its sublethal effects on detoxification enzymes (carboxylesterases (CarEs), glutathione S-transferases (GSTs), and 7-ethoxycoumarin O-deethylase (ECOD)) in zebrafish (Danio rerio) were investigated. The results indicated that the 24-h LC50 of fipronil for zebrafish was 220.4
Thomas G Shelton
Journal of economic entomology, 106(5), 2160-2166 (2013-11-15)
A small-plot field trial was conducted to examine the area of influence of fipronil at incremental distances away from treated plots on the Harrison Experimental Forest near Saucier, MS. Small treated (water and fipronil) plots were surrounded by untreated wooden
Grzegorz Buczkowski et al.
Scientific reports, 9(1), 19495-19495 (2019-12-22)
Invasive ants are major agricultural and urban pests and a significant concern in conservation areas. Despite long history of control and eradication efforts, invasive ants continue to spread around the globe driven by a multitude of synergistic factors. Lack of
Christine Baker et al.
Veterinary parasitology, 202(1-2), 54-58 (2014-04-08)
The efficacy of a novel topical combination of fipronil 8.3% (w/v), (S)-methoprene 10% (w/v), eprinomectin 0.4% (w/v) and praziquantel 8.3% (w/v) (BROADLINE(®)) was tested against adult and immature stages of Ctenocephalides felis fleas in six studies. For that purpose, fleas
Lilia Araujo et al.
Environmental monitoring and assessment, 185(12), 10225-10233 (2013-07-28)
An analytical method for the determination of diflufenican, mepanipyrim, pretilachlor, and fipronil in water samples was developed using single drop microextraction in the direct immersion mode and gas chromatography-mass spectrometry. A factorial fractionated design of type 2(6-1) at two levels
Joseph B Prullage et al.
Veterinary parasitology, 202(1-2), 30-33 (2014-04-08)
Four studies were conducted to examine the efficacy of a novel topical combination of fipronil, (S)-methoprene, eprinomectin, and praziquantel (BROADLINE(®), Merial) against Ancylostoma tubaeforme and Ancylostoma braziliense hookworms of cats. In each study, purpose-bred cats were randomly assigned to treatment
Brian S Anderson et al.
Environmental toxicology and chemistry, 35(12), 3124-3134 (2016-05-05)
Contamination and toxicity associated with urban storm water runoff are a growing concern because of the potential impacts on receiving systems. California water regulators are mandating implementation of green infrastructure as part of new urban development projects to treat storm
W L A Osbrink et al.
Journal of economic entomology, 107(2), 727-740 (2014-04-30)
This field study investigated the colony effect of a fipronil spot treatment applied to active infestations of Formosan subterranean termite, Coptotermes formosanus Shiraki. Spot treatments were applied to a single active independent monitor from each of four colonies in which
M K Rust et al.
Journal of medical entomology, 51(3), 638-643 (2014-06-06)
The monitoring of the susceptibility offleas to insecticides has typically been conducted by exposing adults on treated surfaces. Other methods such as topical applications of insecticides to adults and larval bioassays on treated rearing media have been developed. Unfortunately, baseline
Hahyun Park et al.
Journal of hazardous materials, 385, 121531-121531 (2019-11-17)
Fipronil has been widely used in agriculture to prevent aggressive insects from damaging agricultural products. Fipronil residues circulate in the environment and they have been detected in non-targeted organisms in aquatic environments. To study the effect of fipronil toxicity on
Martin Knaus et al.
Veterinary parasitology, 202(1-2), 45-48 (2014-04-08)
Infection with urinary capillarid bladder worms has been observed in cats worldwide. Although considered as generally causing no or little harm, infection with urinary capillarids may be associated with clinical disease which requires an appropriate treatment including the use of
Martin Knaus et al.
Veterinary parasitology, 202(1-2), 64-68 (2014-04-08)
The efficacy of a novel topical combination of fipronil 8.3% w/v, (S)-methoprene 10% w/v, eprinomectin 0.4% w/v, and praziquantel 8.3% w/v (BROADLINE(®),(1) Merial) against larval and adult Aelurostrongylus abstrusus lungworms in cats was assessed in a controlled laboratory study. The
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