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Elisabeth Lenz et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 96, 44-52 (2015-07-22)
Co-amorphous drug formulations provide the possibility to stabilize a drug in its amorphous form by interactions with low molecular weight compounds, e.g. amino acids. Recent studies have shown the feasibility of spray drying as a technique to manufacture co-amorphous indomethacin-arginine
N Jedinger et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 92, 83-95 (2015-03-04)
The objective of the present study was to investigate interactions between alcohol and hot-melt extruded pellets and the resulting drug release behavior. The pellets were composed of vegetable calcium stearate as matrix carrier and paracetamol or codeine phosphate as model
Mary-Rus Martínez-Cuenca et al.
PloS one, 10(7), e0134372-e0134372 (2015-08-01)
This work provides insight into several mechanisms involved in boron (B) regulation pathway in response to high B conditions in Citrus. The study was carried out in Citrus macrophylla W. (Cm) seedlings cultured "in vitro" in media with 50 or
Ayman M El-Amin et al.
The journal of adhesive dentistry, 17(2), 163-168 (2015-04-02)
To investigate the effect of pre-repair aging periods and intermediate adhesive systems based on different monomers on the repair bond strength of silorane-based resin composite. A total of 32 Filtek P90 (3M ESPE) substrate specimens (4 mm diameter and 4
Imola Plangár et al.
Ideggyogyaszati szemle, 66(11-12), 407-414 (2014-02-22)
The available scientific data indicate that the pathomechanism of Parkinson's disease (PD) involves the accumulation of endogenous and exogenous toxic substances. The disruption of the proper functioning of certain transporters in the blood-brain barrier and in the blood-cerebrospinal fluid barrier
Mónica Moreno et al.
Electrophoresis, 36(16), 1945-1952 (2015-06-03)
This work reports on the positive effects observed upon both the separation and analytical signals in electrophoretic separations of selected phenolic compounds when using aqueous BGE containing carbon nanotubes (CNTs) in connection to electrochemical detection (ECD). The influence of the
Xiaoding Wei et al.
Nature communications, 6, 8029-8029 (2015-08-21)
The ability to bias chemical reaction pathways is a fundamental goal for chemists and material scientists to produce innovative materials. Recently, two-dimensional materials have emerged as potential platforms for exploring novel mechanically activated chemical reactions. Here we report a mechanochemical
Alain Wuethrich et al.
Journal of chromatography. A, 1401, 84-88 (2015-05-27)
Sample preparation by electrophoretic concentration, followed by analysis using sweeping-micellar electrokinetic chromatography, was studied as a green and simple analytical strategy for the trace analysis of cationic drugs in water samples. Electrophoretic concentration was conducted using 50 mmol/L ammonium acetate
Amirfarhang Miresmaeili et al.
American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics, 146(2), 161-165 (2014-08-03)
In this study, we aimed to determine the effect of carbon dioxide laser irradiation on enamel surface microhardness. In this single-blind interventional clinical trial, 16 patients needing at least 2 premolars extracted for orthodontic purposes participated. In each subject, 1
Markus Oehlerich et al.
Rapid communications in mass spectrometry : RCM, 27(6), 707-712 (2013-02-19)
Stable isotope ratio (δ(13)C, δ(18)O values) analyses of carbonates can be biased by CO(2) release from organic impurities. This is most critical for carbonate isotope analyses from bulk sediments containing comparably high amounts of organic matter (OM). Several methods have
Rong-Cing Huang et al.
ACS applied materials & interfaces, 6(24), 21780-21787 (2014-04-16)
In this study, we developed a label-free, ultrasensitive graphene oxide (GO)-based probe for the detection of oligonucleotides by laser desorption/ionization mass spectrometry (LDI-MS). On the basis of simple π-π stacking and electrostatic interactions between rhodamine 6G (R6G) and GO, we
Fabian Soltermann et al.
Water research, 58, 258-268 (2014-04-29)
Trichloramine is a hazardous disinfection by-product, which is present in chlorinated swimming pools. Although it is primarily taken up by inhalation, the concentration in pool water is important to monitor pool water quality and to assess trichloramine mitigation strategies. To
Ayse Avci et al.
Bioresource technology, 130, 603-612 (2013-01-22)
Dilute H(3)PO(4) (0.0-2.0%, v/v) was used to pretreat corn stover (10%, w/w) for conversion to ethanol. Pretreatment conditions were optimized for temperature, acid loading, and time using central composite design. Optimal pretreatment conditions were chosen to promote sugar yields following
Hiroshi Nogawa et al.
Journal of oral science, 57(1), 17-24 (2015-03-27)
The purpose of the present study is evaluation of bonding durability of tri-n-butylborane (TBB) initiated resin without 4-methacryloyloxyethyl trimellitate anhydride (4-META) joined to human enamel. Ground human enamel was bonded with TBB resin under six surface conditions: 1) as ground
Sudhakar Babu Kondra et al.
Journal of chromatographic science, 52(8), 880-885 (2013-09-14)
A novel stability-indicating ultra performance liquid chromatographic (UPLC) method has been developed for quantitative determination of nilotinib hydrochloride in active pharmaceutical ingredients along with four impurities (imp-1, imp-2, imp-3 and imp-4). The method is applicable to the quantification of related
Daniela Sarahí Gutiérrez-Torres et al.
BioMed research international, 2015, 175025-175025 (2015-09-05)
Inorganic arsenic (iAs) exposure induces a decrease in glucose type 4 transporter (GLUT4) expression on the adipocyte membrane, which may be related to premature births and low birth weight infants in women exposed to iAs at reproductive age. The aim
Sami T Tuomivaara et al.
Carbohydrate research, 402, 56-66 (2014-12-17)
Xyloglucans are structurally complex plant cell wall polysaccharides that are involved in cell growth and expansion, energy metabolism, and signaling. Determining the structure-function relationships of xyloglucans would benefit from the availability of a comprehensive and structurally diverse collection of rigorously
Hongqiang Chen et al.
Fitoterapia, 95, 133-138 (2014-03-20)
Three new jatrophane diterpenes (1-3), an unreported spectroscopic data jatrophane diterpenene (4), and nine known analogues (5-13) have been isolated from the whole plants of Euphorbia helioscopia. Their structures were established by detailed spectroscopic data analyses (IR, ESIMS, HR-ESIMS, and
Miao Yu et al.
Journal of chromatographic science, 53(4), 478-483 (2014-07-02)
A new method for the determination of six compounds, chlorogenic acid, rutin, nicotiflorin, hederacoside C, hederasaponin B and α-hederin, in ivy leaf extracts using high-performance liquid chromatography with diode array detector was developed. The chromatographic separation was performed on a
Erik Anderson et al.
Bioresource technology, 200, 153-160 (2015-10-20)
Scum is an oily waste stream of the wastewater treatment process that can be used to produce biodiesel. Combining acid hydrolysis and solvent extraction, a free fatty acid and acyl-glycerol rich product was produced. Free fatty acids (FFAs) present were
Hüdai I Taşdemir et al.
Die Pharmazie, 69(9), 648-654 (2014-10-03)
The electrochemistry of moexipril (MOE) was studied by electrochemical methods with theoretical calculations performed at B3LYP/6-31 + G (d)//AM1. Cyclic voltammetric studies were carried out based on a reversible and adsorption-controlled reduction peak at -1.35 V on a hanging mercury
Ronak Savla et al.
Pharmaceutical research, 31(12), 3487-3502 (2014-06-13)
Design and synthesis of a tumor responsive nanoparticle-based system for imaging and treatment of various cancers. Manganese oxide nanoparticles (Mn3O4 NPs) were synthesized and modified with LHRH targeting peptide or anti-melanoma antibodies (cancer targeting moieties) and a MMP2 cleavable peptide
Yinyue Tan et al.
Environmental science and pollution research international, 22(1), 609-617 (2014-08-07)
Ciprofloxacin (CIP) can be strongly adsorbed by ferric oxides, but some influencing factors, such as multivalent cations and soil organic matter, have not been evaluated extensively. In this study, the interaction between CIP and four divalent metals (Ca, Cd, Cu
Zizwe A Chase et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 21(46), 16541-16546 (2015-09-26)
The state of Ni supported on HZSM-5 zeolite, silica, and sulfonated carbon was studied during aqueous-phase catalysis of phenol hydrodeoxygenation using in situ extended X-ray absorption fine structure spectroscopy. On sulfonated carbon and HZSM-5 supports, NiO and Ni(OH)2 were readily
Weidang Wu et al.
Cancer science, 106(6), 747-756 (2015-04-14)
L-type amino acid transporter 1 (LAT1), overexpressed on the membrane of various tumor cells, is a potential target for tumor-targeting therapy. This study aimed to develop a LAT1-mediated chemotherapeutic agent. We screened doxorubicin modified by seven different large neutral amino
Massimiliano Sgroi et al.
Water research, 70, 174-183 (2014-12-22)
Full-scale experiments to evaluate N-nitrosodimethylamine (NDMA) formation and attenuation were performed within an advanced indirect potable reuse (IPR) treatment system, which includes, sequentially: chloramination for membrane fouling control, microfiltration (MF), reverse osmosis (RO), ultraviolet irradiation with hydrogen peroxide (UV/H₂O₂), final
Gamal ElMasry et al.
Talanta, 143, 145-156 (2015-06-17)
The current study attempted to provide a convenient, non-invasive and time-saving method to estimate the freshness of intact horse mackerel (Trachurus japonicus) fish in a frozen state using autofluorescence spectroscopy in tandem with multivariate analysis of fluorescence excitation-emission matrices (EEM).
Elena Sánchez-López et al.
Journal of chromatography. A, 1363, 356-362 (2014-08-03)
Two chiral methodologies were developed by capillary electrophoresis (CE) with UV and mass spectrometry (MS) detection to ensure the quality control of the drug duloxetine, commercialized as a pure enantiomer. Both methods were optimized to achieve a high baseline enantioresolution
Manabu Ueno et al.
Nature communications, 6, 6332-6332 (2015-03-11)
Alveolar macrophages play a crucial role in the pathogenesis of emphysema, for which there is currently no effective treatment. Bisphosphonates are widely used to treat osteoclast-mediated bone diseases. Here we show that delivery of the nitrogen-containing bisphosphonate alendronate via aerosol
A minimally invasive smile restoration. A case report describing a multitechnique approach over time.
Renato Herman Sundfeld et al.
Dentistry today, 31(12), 86-89 (2013-01-29)
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