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ADC and bioconjugation

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Staudinger Ligation
Azides react with triarylphosphines to form iminophophoranes, a chemoselective synthetic method known as Staudinger Ligation.
Polybrene® Technical Bulletin
Polybrene® neutralizes red blood cell charge, a vital anti-heparin agent in various laboratory applications.
Click Chemistry in Drug Discovery
Drug discovery process by utilizing chemistry reaction of Cu(I)-catalyzed Huisgen 1,3-dipolar cycloaddition of terminal alkynes with organoazides to yield 1,4-disubstituted 1,2,3-triazoles.
Introduction to Click Chemistry
Click chemistry is an approach to the synthesis of drug-like molecules that can accelerate the drug discovery process by using a few practical and reliable reactions.
Copper-Free Click Chemistry
Copper-free click chemistry is an alternative approach to click chemistry that proceeds at a lower activation barrier and is free of cytotoxic transition metal catalysts.
Trifunctional Probe Building Blocks
In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.
Triazolylphenylglyoxal Reagents: Bioconjugation
Chemical ligation modifies biological macromolecules for biotech and medicine, expanding functional material development.
Guanylation of Amines
Introduce guanidinyl group using guanylating reagents like bis(tert-butoxycarbonyl)thiopseudourea, polymer-bound, from substituted amines.
GlycoProfile™ Azido Sugars
GlycoProfile™ Azido Sugar portfolio offers peracetylated azido sugars for glycan structure modification via chemical or biosynthetic pathways.