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Smart Oligonucleotide Delivery by Multifunctional Block Copolymers
Kanjiro Miyata (The University of Tokyo, Japan) provides insights on the rational design of polymeric materials for “smart” oligonucleotide delivery.
Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture
Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic
Halloysite Nanotubes Applications in Nanomaterials Research
Halloysite Nanotubes in Nanomaterials Research. Halloysite, a naturally occurring aluminosilicate nanotube, has been undeservedly forgotten.
RESOMER® Biodegradable Polymers for Medical Device Applications Research
Find use of RESOMER® biodegradable polymers in medical device applications research.
RESOMER® - Biodegradable Polymers for Sutures, Medical Devices, Drug Delivery Systems and Tissue Engineering
Interest in utilizing biodegradable polymers for biomedical applications has grown since the 1960s.
Chitosan Biopolymer from Fungal Fermentation for Delivery of Chemotherapeutic Agents
Chitosan is a naturally occurring polysaccharide ideally suited for use in medical supplies, devices, therapeutics, and diagnostics. The unique natural characteristics of chitosan include its cationic, biocompatible, biodegradable, non-toxic, non-immunogenic, and antimicrobial properties.
Polyethylene Glycol Building Blocks for PEGylation presents an article regarding Polyethylene Glycol Building Blocks for PEGylation.
Chemistry in (Bio)Materials Science
"Click" Chemistry in (Bio)Materials Science
Biodegradable Polyester Based Nanoparticle Formation by Miniemulsion Technique
Aliphatic polyesters such as polylactide, poly(lactide-co-glycolide) and polycaprolactone, as well as their copolymers, represent a diverse family of synthetic biodegradable polymers that have been widely explored for medical uses and are commercially available.
Fabrication of Drug-loaded Microparticles Using Hydrogel Technology and Recent Innovation in Automation
Microparticle drug delivery systems have been extensively researched and applied to a wide variety of pharmaceutical and medical applications due to a number of advantages including injectability, local applicability to target tissues and sites, and controlled drug delivery over a
Poly(Glycerol Sebacate) in Tissue Engineering and Regenerative Medicine
The world of commercial biomaterials has stagnated over the past 30 years as few materials have successfully transitioned from the bench to clinical use. Synthetic aliphatic polyesters have continued to dominate the field of resorbable biomaterials due to their long
Applications of Glucose Polymers in the Synthesis of Diagnostic and Drug Delivery Nanoparticles
Dmitri Simberg (University of Colorado Anschutz Medical Campus, USA) reviews the used of dextran and cyclodextrin for the synthesis of nanoparticles used in drug delivery applications.
Injectable Hydrogels for Cell Delivery and Tissue Regeneration
The use of hydrogel-based biomaterials for the delivery and recruitment of cells to promote tissue regeneration in the body is of growing interest. This article discussed the application of hydrogels in cell delivery and tissue regeneration.
Functional RAFT Polymers for Biomedical Applications
Reversible addition–fragmentation chain transfer (RAFT) polymerization is rapidly moving to the forefront in construction of drug and gene delivery vehicles.
Applications of Y-Shape Peg Derivatives for Drug Delivery
The immune system protects the body from disease by resisting the invasion of foreign molecules into its cells, for example peptides and proteins are hydrolyzed by proteolytic enzymes; nucleic acids are hydrolyzed by nucleases; and most small molecules are eliminated
Delivery of Nucleic Acids Using Polymers
Delivery of Nucleic Acids Using Polymers
Polymersomes for Drug Delivery
The development of drugs that target specific locations within the human body remains one of the greatest challenges in biomedicine today.
Drug Delivery FAQs
Find answers to common questions about drug delivery. Review important points about encapsulation efficiency and loading capacity.
Biodegradable Aliphatic Polyesters for Drug Delivery
Innovations in polymer technology have had a significant impact on the advancement of novel drug delivery systems.
Functionalized PEI and Its Role in Gene Therapy
Gene therapy has become one of the most discussed techniques in biomedical research in recent years.
Reversible Addition Fragmentation Chain Transfer (RAFT) Polymerization
RAFT (Reversible Addition Fragmentation chain Transfer) polymerization is a reversible deactivation radical polymerization (RDRP) and one of the more versatile methods for providing living characteristics to radical polymerization.
Functional Biomaterials Synthesized by Double-Head Polymerization Agents
Over the past two decades, the rapid advance of controlled living polymerization (CLP) techniques.
Microfluidic-Assisted Manufacturing of Materials for Nanomedicine
Professor Nicola Tirelli (Istituto Italiano di Tecnologia, Italy) highlights the microfluidic-assisted method for fabricating well-defined and reproducible nanoparticles for drug delivery research.
Silica-coated Gold Nanoparticles: Surface Chemistry, Properties, Benefits and Applications
In the past few decades, research and commercial use of gold nanoparticles has rapidly expanded into fields extending from biomedical engineering to photovoltaics. Most applications take advantage of the excellent optical properties of gold nanoparticles, which can be fine-tuned by
Gold Nanoparticles: Properties and Applications
Gold (Au) nanoparticles have tunable optical and electronic properties and are used in a number of applications including photovoltaics, sensors, drug delivery & catalysis.
Poly(2-Oxazoline)s: The Versatile Polymer Platform for Biomedicine
The introduction of polymers into the biomedical field has opened new avenues in tissue engineering, implant design, biosensing, and drug delivery.
Layer-by-Layer (LbL) Assembly, A "Gentle Yet Flexible" Method Toward Functional Biomaterials
Recently, layer-by-layer (LbL) assembly has emerged as a versatile, gentle and, simple method for immobilization of functional molecules in an easily controllable thin film morphology.1,2 In this short review, we introduce recent advances in functional systems fabricated by using the
Chitosan-based Biomaterials
Chitin, a natural polysaccharide, is the second most abundant natural biopolymer in the world, after cellulose.
Silicon Carbide: The Return of an Old Friend
In recent years silicon carbide, SiC, has re-emerged as a vital technological material that is crucial in many materials and engineering applications.
Collagen in Gene Delivery Applications
Collagen-based delivery systems effectively deliver a range of viral and non-viral gene carriers by providing spatiotemporal control over delivery and reducing degradation rates and immune responses.
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