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CRISPR/Cas9 Products and Services
Synonym: CRISPR, CRISPRs, Cas9, Crispr RNA, Crispr/Cas System, Synthetic CRISPR, crRNA, tracrRNA
SMCxPRO™ Immunoassay Instrument and SMC™ Kits
High Sensitivity Protein Measurement at the fg/mL level Synonym: SMC, Singulex, single molecule counting, xPRO
DNA Oligos in Tubes
DNA Oligos in Tubes. Product VC00021
Processing Small Tissue or Cell Samples using Sample Grinding Kit
Sample Grinding Kit from GE Healthcare is designed to disrupt cell or tissue samples for protein extraction.
Calculators & Apps
Calculators & Apps
Asia Pacific
Asia Pacific Region
Americas
Americas region
Evaluation of LCMSMS Deuterium Scrambling in Clinically Significant Small Molecules
LC-MS/MS is a powerful tool that brings numerous benefits to the clinical sample analysis arena. However, due to the complexity of the instrumentation there are some unique challenges that also accompany these benefits. Even following sample extraction and cleanup, matrix
Ascentis ® Express HILIC U/HPLC Columns
For separation of polar compounds including polar neutrals, polar acids, and polar and non-polar basic amines use our Ascentis® Express HILIC column.
Detection, Measurement and Regulation of NOGE (Novolac Glycidyl Ethers) and Other Packaging-Derived Epoxy Compounds In Food Products
Detection, Measurement and Regulation of NOGE (Novolac Glycidyl Ethers) and Other Packaging-Derived Epoxy Compounds In Food Products
HPLC Analysis of Methylphenobarbital (Mephobarbital) Enantiomers on Astec® CHIROBIOTIC® V
Separation of Mephobarbital, United States Pharmacopeia (USP) Reference Standard
UHPLC Analysis of Conjugated Estrogens on Ascentis ® Express C18
Separation of Estriol 3-(β-D-glucuronide) sodium salt; β-Estradiol 3-(β-D-glucuronide) 17-sulfate dipotassium salt; Estriol 3-sulfate sodium salt; β-Estradiol 3,17-disulfate dipotassium salt, ≥95%; β-Estradiol 17-(β-D-glucuronide) sodium salt; β-Estradiol 3-(β-D-glucuronide) sodium salt; Estrone 3-(β-D-glucuronide) sodium salt; β-Estradiol 3-sulfate sodium salt, ≥93%; Estriol, ≥97%; Estrone
HPLC Analysis of Proteins on Proteomix® SCX-NP5
Separation of Ribonuclease A from bovine pancreas, Type I-A, powder, ≥60% RNase A basis (SDS-PAGE), ≥50 Kunitz units/mg protein; α-Chymotrypsinogen A from bovine pancreas, essentially salt-free, lyophilized powder; Cytochrome c from bovine heart, ≥95% based on Mol. Wt. 12,327 basis;
Ascentis® Express UHPLC Columns with 2.0 μm Fused-Core Particles
Ascentis® Express columns with 2.0 μm particles show comparable efficiency at a significantly lower pressure than competitor columns that use smaller particles.
An LC/MS Peptide Standard for Rapid System Suitability Assessment and Retention Time Translation Across LC/MS Platforms
Standards are critical in liquid chromatography/mass spectrometry (LC/MS) based proteomics to ensure optimal and consistent system performance before, during, and after sample analysis.
HPLC Analysis of Sugars by HILIC Chromatography using Ascentis® Express OH-5 Column with ELSD Detection
Separation of Dextrose, Pharmaceutical Secondary Standard; Certified Reference Material; Sucrose; Maltitol, Pharmaceutical Secondary Standard; Certified Reference Material
IVD Lateral Flow – Sample, Conjugate and Absorbent Pad Basics
IVD Lateral Flow – Sample, Conjugate and Absorbent Pad Basics
GC/MS/MS Analysis of Bisphenol A (BPA) in a Fruit Flavored Energy Drink on the SLB-PAHms Column After SPME Using an Overcoated SPME Fiber
GC/MS/MS Analysis of Bisphenol A (BPA) in a Fruit Flavored Energy Drink on the SLB-PAHms Column After SPME Using an Overcoated SPME Fiber
Supelco Preparative HPLC products for Pharmaceutical Development and Production
Supelco Preparative HPLC products for Pharmaceutical Development and Production
LC/MS Analysis of Nicotine and Metabolites on Kromasil® Eternity™ C18 (Analyte Set 1)
Separation of (+)-Anabasine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; S(−)-Nicotine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material; (S)-N-Nitrosoanabasine (NAB) solution, 1.0 mg/mL in methanol, ampule
A Quantitative Mass Spectrometry-based Approach for Identifying Protein Kinase Clients and Quantifying Kinase Activity
A quantitative mass spectrometry-based approach for identifying protein kinase clients and quantifying kinase activity
HPLC Analysis of Xanthines on Purospher® STAR RP-18 endcapped
Xanthine is a purine base found in most human body tissues and fluids as well as in other organisms. Methylated xanthines (methylxanthines), which include caffeine, paraxanthine, theobromine, and theophylline, commonly used for their effects as mild stiµlants and as bronchodilators
Ascentis® Express RP-Amide HPLC Columns
Sigma-Aldrich.com presents an article about innovative particle technology and RP-Amide bonding chemistry provide the benefits of speed, resolution, selectivity, aqueous stability, and improved peak shape for bases.
How to Extend Liquid Chromatography Column Life: Regenerate or Use Guard Columns
What is causing aging of a column? Is the regeneration/washing of the column a reasonable approach to extend the lifetime of a column? What are the risks & challenges? Learn more in this article.
BIOshell™ Glycan U/HPLC Columns
The BIOshell™ Glycan column is ideal for the separation and quantitation of isolated glycans using the HILIC method for accurate glycoprotein analysis.
Dyestuff Analyses on Historic Objects by LC-ESI-MS/MS Using a Superspher RP-18 HPLC Column
In this study, LC-ESI-MS/MS under reversed phase conditions using a Superspher RP-18 column is applied to analyze dyestuffs of a reddish historic textile from South America.
HPLC Analysis of Polyglutamate Metabolites of Methotrexate on TSKgel® NH2-100 and ODS-100V
Separation of Methotrexate (MTX)-PG; Methotrexate (MTX)-PG2; Methotrexate (MTX)-PG3 ; Methotrexate (MTX)-PG4; Methotrexate (MTX)-PG5; Methotrexate (MTX)-PG6; Methotrexate (MTX)-PG7
High Resolution and High Efficiency Separations of mAbs and ADCs Using Proteomix HIC Columns
Hydrophobic interaction chromatography, a protein separation technique, has been commonly used as an orthogonal method to SEC and ion exchange for the characterization of mAbs.
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