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Robert Budinsky et al.
Environmental and molecular mutagenesis, 54(9), 755-768 (2013-09-17)
Vinyl acetate monomer (VAM) produced rat nasal tumors at concentrations in the hundreds of parts per million. However, VAM is weakly genotoxic in vitro and shows no genotoxicity in vivo. A European Union Risk Assessment concluded that VAM's hydrolysis to...
Jinjing Wang et al.
Applied biochemistry and biotechnology, 169(3), 1016-1025 (2013-01-09)
Higher acetaldehyde concentration in beer is one of the main concerns of current beer industry in China. Acetaldehyde is always synthesized during beer brewing by the metabolism of yeast. Here, using ethanol as the sole carbon source and 4-methylpyrazole as...
Tetsushi Azuma et al.
Journal of plant physiology, 170(13), 1158-1164 (2013-04-18)
Gravitropic curvature of pulvini of wheat and oat stem segments gradually declined with decreasing atmospheric O₂ concentration and was almost completely blocked under anoxia, whereas that of rice stem segments was enhanced under hypoxia and anoxia. Anoxia substantially increased the...
Rubén del Barrio-Galán et al.
Food chemistry, 179, 116-126 (2015-02-28)
The effect of high levels of the polysaccharide Saccharomyces cerevisiae yeast strain (HPS) and another conventional yeast strain (FERM) on the polysaccharide and phenolic composition of Syrah red wines during alcoholic fermentation and subsequent aging on lees, with or without...
Takuya Kitamura et al.
The Biochemical journal, 465(1), 79-87 (2014-10-07)
Aldehyde dehydrogenases (ALDHs) catalyse the conversion of toxic aldehydes into non-toxic carboxylic acids. Of the 21 ALDHs in mice, it is the ALDH3 family members (ALDH3A1, ALDH3A2, ALDH3B1, ALDH3B2 and ALDH3B3) that are responsible for the removal of lipid-derived aldehydes....
Kadri Aller et al.
Microbiology (Reading, England), 161(Pt 5), 1073-1080 (2015-03-07)
Lactococcus lactis is an important lactic acid starter for food production as well as a cell factory for production of food grade additives, among which natural flavour production is one of the main interests of food producers. Flavour production is...
Yannai S
Dictionary of Food Compounds with CD-ROM: Additives, Flavors, and Ingredients, 7-7 (2012)
Olivier Autin et al.
Water research, 47(6), 2041-2049 (2013-02-14)
The impact of background constituents on the degradation of trace levels of micropollutants by two advanced oxidation processes: UV/H₂O₂ and UV/TiO₂ was studied. Experimental results demonstrated that the background scavenging rate rather than the concentration of micropollutant controls the required...
Nina Baumjohann et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 32(9), 1552-1560 (2015-08-11)
During storage, acetaldehyde migration from polyethylene terephthalate (PET) bottles can affect the quality of mineral water even in the low µg l(-1) range negatively, as it features a fruity or plastic-like off-flavour. For a sensitive and fast analysis of acetaldehyde...
Helene Hopfer et al.
Molecules (Basel, Switzerland), 20(5), 8453-8483 (2015-05-20)
Twenty-seven commercial Californian Cabernet Sauvignon wines of different quality categories were analyzed with sensory and chemical methods. Correlations between five quality proxies-points awarded during a wine competition, wine expert scores, retail price, vintage, and wine region-were correlated to sensory attributes...
Valeria Romanazzi et al.
Environmental toxicology and pharmacology, 36(2), 378-383 (2013-06-05)
Acetaldehyde (AA) is the main metabolic product in ethanol metabolism, although it can also derive from sources of airborne pollution. As a typical aldehyde, AA is able to react with a variety of molecular targets, including DNA and protein. This...
Taichi Yamazaki et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 31(6), 463-468 (2015-06-13)
Acetaldehyde is regulated as a toxic substance in various fields, and the method for monitoring or analysis of acetaldehyde is important. However, handling is difficult because of the high reactivity and low boiling point of acetaldehyde. Therefore, a reference material...
Tengfei Jiang et al.
Journal of colloid and interface science, 405, 242-248 (2013-06-20)
In this study, the p-Cu2O/n-Cu2O homojunction film was prepared by a simple two-step electrodeposition method. The photoinduced charge transfer process in p-Cu2O/n-Cu2O homojunction film was studied using surface photovoltage technique. Then, the p-Cu2O/n-Cu2O homojunction film was assembled into a photoelectric...
Hyeong-Geug Kim et al.
World journal of gastroenterology, 20(42), 15703-15714 (2014-11-18)
To evaluate protective effects of Chunggan extract (CGX), a traditional herbal formula, under 4 wk of alcohol consumption-induced liver injury. Male Sprague-Dawley Rats were orally administered 30% ethanol daily for 4 wk with or without CGX. The pharmaceutical properties were...
Soichiro Yamabe et al.
The FEBS journal, 280(7), 1617-1629 (2013-02-05)
Mammalian cells attempt to maintain their homeostasis under endoplasmic reticulum (ER) stress. If the stress cannot be alleviated, cells are led to apoptosis through induction of C/EBP homologous protein (CHOP). ER stress is provoked in osteoarthritis chondrocytes, and intracellular accumulation...
Gabriel B Akanni et al.
Journal of the science of food and agriculture, 95(5), 1094-1102 (2014-11-06)
The cladodes of Opuntia ficus-indica (prickly pear cactus) have a low protein content; for use as a balanced feed, supplementation with other protein sources is therefore desirable. We investigated protein enrichment by cultivation of the yeasts Candida utilis and Kluyveromyces...
Danielle D Cloutier et al.
Applied and environmental microbiology, 81(15), 4904-4913 (2015-05-17)
Microbial communities within beach sand play a key role in nutrient cycling and are important to the nearshore ecosystem function. Escherichia coli and enterococci, two common indicators of fecal pollution, have been shown to persist in the beach sand, but...
Ikuo Ueta et al.
Analytical and bioanalytical chemistry, 407(3), 899-905 (2014-09-10)
A novel miniaturized sample extraction capillary was developed to provide a simple and sensitive method for analyzing gaseous formaldehyde (FA) using conventional high-performance liquid chromatography (HPLC). The extraction capillary was prepared by packing silica gel particles in a stainless steel...
Izumi Ujihara et al.
Neuropharmacology, 99, 589-599 (2015-08-25)
The sensation of thirst experienced after heavy alcohol drinking is widely regarded as a consequence of ethanol (EtOH)-induced diuresis, but EtOH in high doses actually induces anti-diuresis. The present study was designed to investigate the introduction mechanism of water and...
Victor R Preedy et al.
Novartis Foundation symposium, 285, 158-177 (2007-06-27)
Alcoholic myopathy is characterized by biochemical and morphological lesions within muscle, ranging from impairment of muscle strength and loss of lean tissue to cellular disturbances and altered gene expression. The chronic form of the disease is five times more common...
Acetaldehyde links alcohol consumption to cancer.
Adrian Burton
The Lancet. Oncology, 6(9), 643-643 (2005-09-16)
Lucía Martí-Prats et al.
Neuropharmacology, 72, 204-214 (2013-05-07)
Recent electrophysiological evidence suggests that ethanol simultaneously exerts opposite effects on the activity of dopamine (DA) neurons in the ventral tegmental area (VTA) through two parallel mechanisms, one promoting and the other reducing the GABA release onto VTA DA neurons....
Travis M Doggett et al.
Alcoholism, clinical and experimental research, 38(9), 2414-2426 (2014-09-27)
Alcohol intoxication can increase inflammation and worsen injury, yet the mechanisms involved are not clear. We investigated whether acute alcohol intoxication increases microvascular permeability and investigated potential signaling mechanisms in endothelial cells that may be involved. Conscious rats received a...
Christoph Hutzler et al.
Archives of toxicology, 88(7), 1295-1308 (2014-06-25)
Electronic (e-)cigarettes have emerged in recent years as putative alternative to conventional tobacco cigarettes. These products do not contain typical carcinogens that are present in tobacco smoke, due to the lack of combustion. However, besides nicotine, hazards can also arise...
W G Brydon et al.
European journal of gastroenterology & hepatology, 8(2), 117-123 (1996-02-01)
To assess the reliability of serum 7 alpha-hydroxy-4-cholesten-3-one (7 alpha-3ox-C) in the differential diagnosis of bile acid induced diarrhoea by comparison with 75selenohomocholyltaurine whole body retention (SeHCAT WBR). One hundred and sixty-four patients with chronic diarrhoea were investigated prospectively in...
V S Shubina et al.
Bulletin of experimental biology and medicine, 154(1), 152-157 (2013-01-19)
We studied the effect of liposome preparation containing taxifolin oligomers and taxifolin conjugates with carbonyl compounds on skin regeneration after chemical burn. The preparations containing flavonoid conjugates intensified regeneration processes and reparation of hair follicles and sebaceous glands after chemical...
Tetsuji Yokoyama et al.
Alcoholism, clinical and experimental research, 29(4), 622-630 (2005-04-19)
Elevated mean corpuscular volume (MCV) is a traditional biological marker for alcohol abuse and alcoholism, but the underlying mechanism is unclear. Three recent epidemiologic studies consistently showed that MCV was elevated by alcohol drinking more markedly among individuals with genetically...
L R G Nieminen et al.
Prostaglandins, leukotrienes, and essential fatty acids, 75(4-5), 309-314 (2006-09-09)
Deficiency in the long-chain omega-3 fatty acid, docosahexaenoic acid (DHA) has been associated with increased corticotropin releasing hormone and may contribute to hypothalamic pituitary axis (HPA) hyperactivity. Elevated levels of the neuroactive steroids, allopregnanolone (3alpha,5alpha-THP) and 3alpha,5alpha-tetrahydrodeoxycorticosterone (THDOC) appear to...
T W Boyden et al.
European journal of pharmacology, 70(4), 571-576 (1981-04-09)
Utilizing a method for perfusion of the in vivo isolated canine testis we have examined basal and human chorionic gonadotropin (hGC)-stimulated testosterone production of testes acutely exposed to ethanol and acetaldehyde. Ethanol infused at concentrations of 0.2 g/dl to 0.6...
H Matsuse et al.
The Journal of allergy and clinical immunology, 108(5), 715-719 (2001-11-03)
We have previously reported that alcohol-induced asthma in Japanese patients is caused by increased blood acetaldehyde concentration resulting from abnormalities of acetaldehyde dehydrogenase 2 (ALDH2) enzyme activity on the basis of ALDH2 genotype differences. The purpose of the present study...
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