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Heidi Contreras et al.
The Journal of biological chemistry, 289(26), 18279-18289 (2014-05-24)
Mycobacterium tuberculosis has evolved various mechanisms by which the bacterium can maintain homeostasis under numerous environmental assaults generated by the host immune response. M. tuberculosis harbors enzymes involved in the oxidative stress response that aid in survival during the production
Belén Max et al.
Applied biochemistry and biotechnology, 168(8), 2268-2284 (2012-10-19)
Debaryomyces hansenii NRRL Y-7426 metabolised ferulic acid into different phenolic compounds using a factorial design where glucose concentration (in the range of 1-20 g/L), peptone concentration (2-20 g/L) and yeast extract concentration (0.2-10 g/L) were the independent variables. The interrelationship between dependent and
José A Piornos et al.
Food research international (Ottawa, Ont.), 123, 317-326 (2019-07-10)
Detection thresholds are used routinely to determine the odour-active compounds in foods. The composition of a food matrix, such as hydrophobicity or solids content, has an impact on the release of flavour compounds, and thus on thresholds. In the case
Ruckminee Mall et al.
Preparative biochemistry & biotechnology, 43(2), 137-151 (2013-01-11)
A soluble and thermostable peroxidase enzyme (POD) was extracted from the leaf of Citrus medica. The enzyme was purified 15.10-fold with a total yield of 28.6% by ammonium sulfate precipitation followed by Sephadex G-100 gel filtration chromatography. The purified enzyme
Kanchan Chauhan et al.
Journal of colloid and interface science, 580, 365-376 (2020-07-21)
The one-pot cascade reaction of naturally occurring enzymes is exciting for highly selective complex reaction and biodegradable approaches. Tamoxifen is the main drug against breast cancer for decades and induces an anticancerous effect upon metabolic activation by cytochrome P450 (CYP450).
Alan P Pollnitz et al.
Journal of agricultural and food chemistry, 52(11), 3244-3252 (2004-05-27)
The deuterium-labeled standards [(2)H(3)]-guaiacol and [(2)H(3)]-4-methylguaiacol were synthesized and utilized in a method employing gas chromatography-mass spectrometry to determine the concentration of guaiacol and 4-methylguaiacol in wine or extracts of oak shavings. The method was combined with previously published methods
Mohammad Hossein Habibi et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 105, 563-568 (2013-01-29)
Computational and spectroscopic properties of a novel Schiff base compound, 3-hydroxy-4-methoxybenzylidene(2-hydroxyphenyl)amine were studied. The crystal structures of the title compound and its corresponding zwitterionic form were analyzed by X-ray diffraction. The presence of N-H, C-O and C=N stretching vibrations in
Carmen Arce et al.
European journal of medicinal chemistry, 55, 475-479 (2012-08-04)
The action of (Z)-N-(2-bromo-5-hydroxy-4-methoxybenzylidene)-2-methylpropan-2-amine oxide (RP6) on rat cortical neurons in culture, under oxygen-glucose-deprivation conditions, is reported. Cortical neurons in culture were treated during 1 h with OGD. After, they were placed under normal conditions during 24 h (reperfusion) in absence and
Tao Liu et al.
The Analyst, 139(17), 4315-4321 (2014-07-06)
The rapid and sensitive detection of Alicyclobacillus acidoterrestris (AA) has become very important due to the frequent occurrence of fruit juice spoilage by AA. In the present study, using guaiacol, both as the metabolic product of AA related to its
A V Sokolov et al.
Free radical research, 49(6), 800-811 (2015-03-13)
Myeloperoxidase (MPO) and eosinophil peroxidase (EPO) are involved in the development of halogenative stress during inflammation. We previously described a complex between MPO and ceruloplasmin (CP). Considering the high structural homology between MPO and EPO, we studied the latter's interaction
Chunhui Ma et al.
Molecules (Basel, Switzerland), 19(12), 20821-20838 (2014-12-17)
Sustainable development of renewable resources is a major challenge globally. Biomass is an important renewable energy source and an alternative to fossil fuels. Pyrolysis of biomass is a promising method for simultaneous production of biochar, bio-oil, pyroligneous acid (PA), and
K M Pruitt et al.
Analytical biochemistry, 191(2), 278-286 (1990-12-01)
Because of the important biological functions of peroxidases, there is growing interest in the measurement of their concentrations in various secretions. At present, there is no standard method which allows for comparisons in reported activities. This report describes procedures which
Toshio Mimurai et al.
Biomedical research (Tokyo, Japan), 26(4), 139-145 (2005-09-13)
Guaiacol, which is a phenolic compound with a methoxy group and used in traditional dental pulp sedation, has the property of inducing cell proliferation. To clarify these mechanisms of guaiacol, this study examined the hydroxyl radical (*OH) scavenging effects of
Satoko Shimizu et al.
Journal of agricultural and food chemistry, 60(26), 6471-6476 (2012-06-15)
The reactivity of lignin during alkaline delignification was quantitatively investigated focusing on the effect of the structural differences between syringyl and guaiacyl aromatic nuclei and between erythro and threo in the side chain of β-O-4 type lignin substructure on the
Nasser M Al-Daghri et al.
BMC complementary and alternative medicine, 12, 202-202 (2012-11-01)
Drugs used both in classical chemotherapy and the more recent targeted therapy do not have cancer cell specificity and, hence, cause severe systemic side effects. Tumors also develop resistance to such drugs due to heterogeneity of cell types and clonal
Simon Döhrmann et al.
Infection and immunity, 82(10), 4011-4020 (2014-07-16)
Streptococcal collagen-like protein 1 (Scl-1) is one of the most highly expressed proteins in the invasive M1T1 serotype group A Streptococcus (GAS), a globally disseminated clone associated with higher risk of severe invasive infections. Previous studies using recombinant Scl-1 protein
Murat Sentürk et al.
Bioorganic & medicinal chemistry, 17(8), 3207-3211 (2009-02-24)
The inhibition of two human cytosolic carbonic anhydrase (hCA, EC isozymes I and II, with a series of phenol derivatives was investigated by using the esterase assay, with 4-nitrophenyl acetate as substrate. 2,6-Dimethylphenol, 2,6-diisopropylphenol (propofol), 2,6-di-t-butylphenol, butylated hydroxytoluene, butylated
Feng Li et al.
Food chemistry, 135(2), 332-337 (2012-08-08)
Hexahydrocurcumin, 1-dehydro-[6]-gingerdione, 6-dehydroshogaol and 6-shogaol were evaluated for their antioxidant and anti-inflammatory activities in the present study. The relative antioxidant potencies of ginger compounds decreased in similar order of 1-dehydro-[6]-gingerdione, hexahydrocurcumin>6-shogaol>6-dehydroshogaol in both 1,1-diphenyl-2-picyrlhydrazyl (DPPH) radical-scavenging and trolox equivalent antioxidant
Eva Ramírez et al.
Journal of agricultural and food chemistry, 62(39), 9569-9575 (2014-09-12)
The main Spanish table olive varieties supplied by different olive cooperatives were investigated for their polyphenol compositions and the endogenous enzymes involved in their transformations during two growing seasons. Olives of the Manzanilla variety had the highest concentration in total
Rebekah C Gullberg et al.
Virology, 475, 219-229 (2014-12-17)
Flaviviruses are 5' capped positive-stranded RNA viruses that replicate their genomes within endoplasmic reticulum-derived vesicles. Flaviviruses are well known to induce oxidative stress late in infection but it is unknown if oxidative stress plays a positive role in the viral
Marija T Popovic-Milenkovic et al.
Acta poloniae pharmaceutica, 71(2), 279-285 (2014-10-03)
Hawthorn has been present for a long time in traditional medicine as antihypertensive, hypolipidemic, anti-inflammatory, gastroprotective, antimicrobial agent. Hawthorn can be used for the cure of stress, nervousness but there is no published paper about actions of Crataegus nigra Wald.
Marina T Tomovic et al.
Acta poloniae pharmaceutica, 72(1), 137-145 (2015-04-09)
Potentilla species have been used in traditional medicine in the treatment of different ailment, disease or malady. Potentilla reptans (P. reptans) has been scarcely studied. The aim of this study was to test antioxidant and anti-inflammatory activity of P. reptans
Alok K Gupta et al.
BMC plant biology, 12, 158-158 (2012-09-04)
Silene latifolia and its pollinator, the noctuid moth Hadena bicruris, represent an open nursery pollination system wherein floral volatiles, especially veratrole (1, 2-dimethoxybenzene), lilac aldehydes, and phenylacetaldehyde are of key importance for floral signaling. Despite the important role of floral
Junqing Zhang et al.
Fitoterapia, 89, 149-156 (2013-04-16)
Isolation, screening and in vivo assays have been used for evaluating anti-diarrhea bioactive of Alpinia oxyphylla. Preliminary experimental results showed that 95% ethanol extract and 90% ethanol elution significantly extended the onset time of diarrhea and reduced the wet feces
Guus van Rossum et al.
ChemSusChem, 7(1), 253-259 (2013-11-23)
The liquefaction of lignocellulosic biomass is studied for the production of liquid (transportation) fuels. The process concept uses a product recycle as a liquefaction medium and produces a bio-oil that can be co-processed in a conventional oil refinery. This all
Rosanna Tofalo et al.
Journal of food science, 77(9), M545-M549 (2012-08-23)
The question if the "Brett character" is a favorable wine attribute is one of the most controversial issues and it is currently addressed by many researches. Actually, the presence of Brettanomyces/Dekkera in wine during barrel aging is often associated to
Burcu Somturk et al.
Dalton transactions (Cambridge, England : 2003), 44(31), 13845-13852 (2015-05-06)
In this study, we report the preparation, catalytic activity and stability of a hybrid nanoflower (hNF) formed from horseradish peroxidase (HRP) enzyme and copper ions (Cu(2+)). We studied the morphology of hNFs as a function of the concentrations of copper
Adam Wu et al.
Dalton transactions (Cambridge, England : 2003), 41(36), 11093-11106 (2012-08-07)
Hydrogenolysis reactions of so-called lignin model dimers using a Ru-xantphos catalyst are presented (xantphos = 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene). For example, of some nine models studied, the alcohol, 2-(2-methoxyphenoxy)-1-phenylethanol (1), with 5 mol% Ru(H)(2)(CO)(PPh(3))(xantphos) (18) in toluene-d(8) at 135 °C for 20 h
Pamela Somers et al.
The Journal of heart valve disease, 24(1), 92-100 (2015-07-18)
Currently, no effective crosslinking reagents are available to treat xenogenic decellularized heart valve matrices. The study aim was to evaluate the crosslinking effect of quercetin, catechin, caffeic acid and tannic acid on porcine aortic valve matrices. Cytotoxicity of the different
Ross C Gruber et al.
Glia, 63(10), 1753-1771 (2015-04-29)
We have previously described reduced myelination and corresponding myelin basic protein (MBP) expression in the central nervous system of Src homology 2 domain-containing protein tyrosine phosphatase 1 (SHP-1) deficient motheaten (me/me) mice compared with normal littermate controls. Deficiency in myelin
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