Residue dynamics of fenamidone and mancozeb on gherkin was evaluated at two different agro climatic zones i.e. at Bangalore (Zone-1) and Dharwad (Zone-2) in the state of Karnataka, India. Two treatments of the combination formulation (fenamidone 10% + mancozeb 50%) were given at the standard dose 150 + 750 g a.i. ha(-1) and double dose 300 + 1,500 g a.i. ha(-1). Initial residue deposits of fenamidone were 0.467 and 0.474 mg kg(-1) at Zone-1 and 2, respectively from standard dose treatment. From double dose treatment they were 0.964 and 0.856 mg kg(-1), respectively. Fenamidone residues persisted for 15 and 10 days and dissipated with the half-life of 4 and 3 days at Zone-1 and 2, respectively. Mancozeb residue deposits on gherkin were 0.383 and 0.428 mg kg(-1) from standard dose and 0.727 and 0.626 mg kg(-1) from double dose treatment at Zone-1 and 2, respectively. Mancozeb residues dissipated with the half-life of 2 and 1 day, respectively. Residues of both fenamidone and mancozeb dissipated faster at Zone-2 compared to Zone-1. The limit of quantification of fenamidone and mancozeb were 0.02 and 0.1 mg kg(-1), respectively in both gherkin and soil. Residues of fenamidone and mancozeb in soil collected on the 20th day from the 2 locations were found to be below quantifiable limit of both fungicides.