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Merck

ACE

angiotensin I converting enzyme

Synonymes:
ACE1, CD143, DCP, DCP1, ICH, MVCD3
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(1636) Summary: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq, May 2010]
  • Mouse(11421) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • Rat(24310) angiotensin I converting enzyme
  • fruit fly(41625) Acetylcholine esterase
  • Zebrafish(565980) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • chicken(419953) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • dog(610668) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • Horse(100064801) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • cow(509484) angiotensin I converting enzyme
  • sheep(554335) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • Domestic Rabbit(100009274) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1

Custom & Knockdown Gene Products

ELISA

Numéro du produit
Description
Espèce(s)
Mouse ACE  ELISA Kit, for serum, plasma and cell culture supernatant,
Espèce(s)
mouse
Human ACE ELISA, for serum, plasma and cell culture supernatants,
Espèce(s)
human

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-ACE antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-ACE antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Monoclonal Anti-CD143 antibody produced in mouse, clone 5-369,
Espèces réactives
human
Application
flow cytometry
Anti-ACE1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse
Application
western blot
Anti-Angiotensin Converting Enzyme Antibody, clone 2E2, culture supernatant, clone 2E2, from mouse,
Espèces réactives
human, rat
Application
western blot

Small Molecule - Inhibitor

Numéro du produit
Description
Espèce(s)
6-Mercaptohexanoic acid, 90%,
Espèce(s)
rat
Ramipril, Pharmaceutical Secondary Standard; Certified Reference Material,
Espèce(s)
human
Lisinopril, ≥98% (HPLC),
Espèce(s)
human
Lisinopril, Pharmaceutical Secondary Standard; Certified Reference Material,
Espèce(s)
human
Ramipril, ≥98% (HPLC),
Espèce(s)
human

Proteins

Numéro du produit
Description
Espèce(s)
Angiotensin Converting Enzyme from porcine kidney, lyophilized powder, ≥10 units/mg protein (Bradford),
Espèce(s)

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human ACE, CTD-2501B8.1,
Espèce(s)
human

Small Molecule - Substrate

Numéro du produit
Description
Espèce(s)
N-Hippuryl-His-Leu hydrate, powder, ≥98% (HPLC),
Espèce(s)
mouse, human, rat
N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly, ,
Espèce(s)
mouse, human, rat
Hippuryl-His-Leu acetate salt, ,
Espèce(s)
mouse, human, rat