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Merck

AOC3

amine oxidase, copper containing 3

Synonymes:
HPAO, SSAO, VAP-1, VAP1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(8639) Summary: This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]
  • Mouse(11754) amine oxidase, copper containing 3
  • Rat(29473) amine oxidase, copper containing 3
  • chicken(420015) amine oxidase, copper containing 3
  • Thale Cress(822169) allene oxide cyclase 3
  • naked mole-rat(101709673) amine oxidase, copper containing 3
  • domestic guinea pig(100721976) amine oxidase, copper containing 3
  • sheep(101112335) amine oxidase, copper containing 3 (vascular adhesion protein 1)
  • cow(281002) amine oxidase, copper containing 3 (vascular adhesion protein 1)
  • Horse(100065718) amine oxidase, copper containing 3 (vascular adhesion protein 1)

Custom & Knockdown Gene Products

ELISA

Numéro du produit
Description
Espèce(s)
Human VAP-1 ELISA, for serum, plasma and cell culture supernatants,
Espèce(s)
human

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-AOC3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-AOC3 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, mouse, rat
Application
ELISA
western blot
Monoclonal Anti-AOC3 antibody produced in mouse, clone 4B8, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunofluorescence

Small Molecule - Inhibitor

Numéro du produit
Description
Espèce(s)
Benzylamine, ReagentPlus®, 99%,
Espèce(s)
mouse, human
4-Fluorobenzylamine, 97%,
Espèce(s)
mouse, human
4-(Trifluoromethyl)benzylamine, 97%,
Espèce(s)
mouse, human
3-Phenyl-1-propylamine, 98%,
Espèce(s)
mouse, human
Benzylamine, purified by redistillation, ≥99.5%,
Espèce(s)
mouse, human

Proteins

Numéro du produit
Description
Espèce(s)
VAP-1 human, recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC),
Espèce(s)
human

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human AOC3,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Aoc3,
Espèce(s)
mouse