APP
amyloid beta (A4) precursor protein
Synonymes:
AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2
Espèce(s):
Human APP (351), Mouse App (11820), Rat App (54226), fruit fly app (39399), chicken APP (374198), dog APP (403407), domestic cat APP (101085564), cow APP (280722), sheep APP (101111593), domestic guinea pig App (100715302)
ID UniProtKB:
ID du gène:
- Human(351) Summary: This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(11820) amyloid beta (A4) precursor protein
- Rat(54226) amyloid beta (A4) precursor protein
- fruit fly(39399) approximated
- chicken(374198) amyloid beta (A4) precursor protein
- dog(403407) amyloid beta (A4) precursor protein
- domestic cat(101085564) amyloid beta (A4) precursor protein
- cow(280722) amyloid beta (A4) precursor protein
- sheep(101111593) amyloid beta (A4) precursor protein
- domestic guinea pig(100715302) amyloid beta (A4) precursor protein
- naked mole-rat(101724743) amyloid beta (A4) precursor protein
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ELISA
Numéro du produit
Description
Espèce(s)
Human APP / Amyloid Beta A4 Protein ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Espèce(s)
human
Small Molecule - Antagonist
Antibodies
Numéro du produit
Description
Espèces réactives
Application
Anticorps anti-APP A4, a. a. 66 à 81 de l′APP {NT}, clone 22C11, clone 22C11, Chemicon®, from mouse,
Espèces réactives
canine, fish, human, monkey, mouse, pig, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anticorps anti-amyloïde β, clone W0-2, clone WO2, from mouse,
Espèces réactives
human, mouse
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-β-Amyloid antibody, Mouse monoclonal, clone BAM-10, ascites fluid,
Espèces réactives
human
Application
ELISA
immunohistochemistry
immunohistochemistry
Anticorps anti-bêta-amyloïde 1-42, Chemicon®, from rabbit,
Espèces réactives
chicken, human, mouse
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
αβ, serum, Chemicon®,
Espèces réactives
eukaryotes, human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
Proteins
Numéro du produit
Description
Espèce(s)