AR
androgen receptor
Synonymes:
AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM
Espèce(s):
Human AR (367), Mouse Ar (11835), Rat Ar (24208), fruit fly ar (44503), Zebrafish ar (100005148), chicken AR (422165), dog AR (403588), domestic cat AR (101081787), domestic cat AR (751827), Horse AR (100033980) ...Plus
ID UniProtKB:
ID du gène:
- Human(367) Summary: The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
- Mouse(11835) androgen receptor
- Rat(24208) androgen receptor
- fruit fly(44503) abdomen rotatum
- Zebrafish(100005148) androgen receptor
- chicken(422165) androgen receptor
- dog(403588) androgen receptor
- domestic cat(101081787) androgen receptor
- domestic cat(751827) androgen receptor
- Horse(100033980) androgen receptor
- cow(280675) androgen receptor
- sheep(443042) androgen receptor
- Goat(100860827) androgen receptor
- Domestic Rabbit(100009193) androgen receptor
- domestic guinea pig(100726891) androgen receptor
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Small Molecule - Activator
Numéro du produit
Description
Espèce(s)
Small Molecule - Agonist
Numéro du produit
Description
Espèce(s)
Testosterone solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human
Testosterone, Pharmaceutical Secondary Standard; Certified Reference Material,
Espèce(s)
human
Methandienone solution, 1.0 mg/mL in 1,2-dimethoxyethane, ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human
Small Molecule - Antagonist
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Description
Espèce(s)
Antibodies
Numéro du produit
Description
Espèces réactives
Application
Anti-Androgen Receptor (C-term) antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP242, affinity isolated antibody,
Espèces réactives
dog, human, mouse, pig, rabbit, rat
Application
immunohistochemistry
Anti-phospho-Androgen Receptor (Ser81) Antibody, rabbit monoclonal, culture supernatant, Upstate®,
Espèces réactives
human
Application
western blot
Anti-Androgen Receptor antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP107, affinity isolated antibody,
Espèces réactives
dog, human, mouse, pig, rat
Application
immunohistochemistry
Anti-AR (n-terminal) antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM254, purified immunoglobulin,
Espèces réactives
human
Application
immunohistochemistry
western blot
western blot
Monoclonal Anti-AR antibody produced in mouse, clone 1G3, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunohistochemistry
proximity ligation assay
western blot
immunohistochemistry
proximity ligation assay
western blot
Small Molecule - Blocker
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Description
Espèce(s)
Small Molecule - Inhibitor
Small Molecule - Ligand
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Description
Espèce(s)