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Merck

C8B

complement component 8, beta polypeptide

Synonymes:
C82
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(732) Summary: This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
  • Mouse(110382) complement component 8, beta polypeptide
  • Rat(313421) complement component 8, beta polypeptide
  • chicken(424669) complement component 8, beta polypeptide
  • Zebrafish(793127) complement component 8, beta polypeptide
  • Horse(100059423) complement component 8, beta polypeptide
  • domestic cat(101099229) complement component 8, beta polypeptide
  • dog(479555) complement component 8, beta polypeptide
  • Domestic Rabbit(100009385) complement component 8, beta polypeptide
  • sheep(101102522) complement component 8, beta polypeptide
  • cow(513217) complement component 8, beta polypeptide
  • naked mole-rat(101696501) complement component 8, beta polypeptide
  • domestic guinea pig(100729610) complement component 8, beta polypeptide

Custom & Knockdown Gene Products

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-C8B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human C8B,
Espèce(s)
human