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Merck

CCR2

chemokine (C-C motif) receptor 2

Synonymes:
CC-CKR-2, CCR-2, CCR2A, CCR2B, CD192, CKR2, CKR2A, CKR2B, CMKBR2, MCP-1-R
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(729230) Summary: This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq, Mar 2009]
  • Mouse(12772) chemokine (C-C motif) receptor 2
  • Rat(60463) chemokine (C-C motif) receptor 2
  • domestic guinea pig(100718888) chemokine (C-C motif) receptor 2
  • naked mole-rat(101724105) chemokine (C-C motif) receptor 2
  • Horse(100048936) chemokine (C-C motif) receptor 2
  • cow(539002) chemokine (C-C motif) receptor 2
  • sheep(101117706) chemokine (C-C motif) receptor 2
  • domestic cat(100049057) chemokine (C-C motif) receptor 2
  • Thale Cress(816705) glycine-rich RNA-binding protein 7
  • Thale Cress(818503) serine/threonine-protein kinase-like protein CCR2
  • Thale Cress(844421) cinnamoyl-CoA reductase
  • chicken(420696) chemokine (C-C motif) receptor 2
  • dog(484790) chemokine (C-C motif) receptor 2

Custom & Knockdown Gene Products

Small Molecule - Antagonist

Numéro du produit
Description
Espèce(s)
Boc-Gln-OH, 98%,
Espèce(s)
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Espèce(s)
rat, human
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Espèce(s)
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Espèce(s)
rat, human
L-Glutamic acid, FCC,
Espèce(s)
rat, human

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anticorps anti-CCR2, clone 8C3.1, clone 8C3.1, from mouse,
Espèces réactives
human
Application
flow cytometry
western blot
Anti-CCR2 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
immunohistochemistry
Anti-Ccr2 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
Anti-CCR2/CKR2 Antibody, clone 10L1L6, Rabbit Monoclonal, ,
Espèces réactives
human, rat
Application
western blot

Small Molecule - Inhibitor

Numéro du produit
Description
Espèce(s)
D-Glutamic acid, ≥99% (TLC),
Espèce(s)
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Espèce(s)
rat, human
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Espèce(s)
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Espèce(s)
rat, human
L-Glutamic acid, FCC,
Espèce(s)
rat, human

Proteins

Numéro du produit
Description
Espèce(s)
ChemiSCREEN CCR2B Membrane Preparation, ,
Espèce(s)
human

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human CCR2,
Espèce(s)
human