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Merck

CDH4

cadherin 4, type 1, R-cadherin (retinal)

Synonymes:
CAD4, RCAD
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(1002) Summary: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
  • Mouse(12561) cadherin 4
  • Rat(114588) cadherin 4
  • naked mole-rat(101726465) cadherin 4, type 1, R-cadherin (retinal)
  • domestic guinea pig(100720758) cadherin 4, type 1, R-cadherin (retinal)
  • sheep(101122716) cadherin 4, type 1, R-cadherin (retinal)
  • chicken(419222) cadherin 4, type 1, R-cadherin (retinal)
  • cow(525796) cadherin 4, type 1, R-cadherin (retinal)
  • dog(100685099) cadherin 4, type 1, R-cadherin (retinal)
  • Zebrafish(30297) cadherin 4, retinal
  • domestic cat(101085708) cadherin 4, type 1, R-cadherin (retinal)

Custom & Knockdown Gene Products

ELISA

Numéro du produit
Description
Espèce(s)
Human Cadherin-4 ELISA, for serum, plasma and cell culture supernatants,
Espèce(s)
human

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-CDH4 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, dog, guinea pig, human, mouse, rat
Application
western blot
Anti R Cadherin Antibody, clone 23GB5055, Rabbit Monoclonal, clone 23GB5055, recombinant rabbit monoclonal, expressed in HEK293 cells,
Espèces réactives
human
Application
flow cytometry
western blot

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human CDH4,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Cdh4,
Espèce(s)
mouse