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Merck

CDKN3

cyclin-dependent kinase inhibitor 3

Synonymes:
CDI1, CIP2, KAP, KAP1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(1033) Summary: The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • Mouse(72391) cyclin-dependent kinase inhibitor 3
  • Rat(289993) cyclin-dependent kinase inhibitor 3
  • dog(609346) cyclin-dependent kinase inhibitor 3
  • sheep(101116234) cyclin-dependent kinase inhibitor 3
  • chicken(423562) cyclin-dependent kinase inhibitor 3
  • cow(615282) cyclin-dependent kinase inhibitor 3
  • domestic guinea pig(100731849) cyclin-dependent kinase inhibitor 3
  • Zebrafish(402796) cyclin-dependent kinase inhibitor 3
  • naked mole-rat(101710612) cyclin-dependent kinase inhibitor 3
  • domestic cat(101100571) cyclin-dependent kinase inhibitor 3

Custom & Knockdown Gene Products

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-CDKN3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence

Small Molecule - Inhibitor

Numéro du produit
Description
Espèce(s)
Roscovitine, ≥98% (TLC),
Espèce(s)
human, mouse, rat
Olomoucine, ≥98% (HPLC),
Espèce(s)
human, rat

Proteins

Numéro du produit
Description
Espèce(s)
CDKN3, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human CDKN3,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Cdkn3,
Espèce(s)
mouse