DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
Synonymes:
NC2-alpha
Espèce(s):
Human DRAP1 (10589), Mouse Drap1 (66556), Rat Drap1 (293674), cow DRAP1 (540345), Goat DRAP1 (100861124), sheep DRAP1 (101111673), dog DRAP1 (476018), domestic cat DRAP1 (101101589), Zebrafish drap1 (321681), domestic guinea pig Drap1 (100734988)
ID UniProtKB:
ID du gène:
- Human(10589) Summary: Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA, TFIIB, and TFIID. DR1 is a repressor that interacts with the TATA-binding protein (TBP) of TFIID and prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the preinitiation complex. The protein encoded by this gene is a corepressor of transcription that interacts with DR1 to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor function and appears to stabilize the TBP-DR1-DNA complex. [provided by RefSeq, Jul 2008]
- Mouse(66556) Dr1 associated protein 1 (negative cofactor 2 alpha)
- Rat(293674) Dr1 associated protein 1 (negative cofactor 2 alpha)
- cow(540345) DR1-associated protein 1 (negative cofactor 2 alpha)
- Goat(100861124) DR1-associated protein 1 (negative cofactor 2 alpha)
- sheep(101111673) DR1-associated protein 1 (negative cofactor 2 alpha)
- dog(476018) DR1-associated protein 1 (negative cofactor 2 alpha)
- domestic cat(101101589) DR1-associated protein 1 (negative cofactor 2 alpha)
- Zebrafish(321681) DR1-associated protein 1 (negative cofactor 2 alpha)
- domestic guinea pig(100734988) DR1-associated protein 1 (negative cofactor 2 alpha)
- naked mole-rat(101706865) DR1-associated protein 1 (negative cofactor 2 alpha)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Numéro du produit
Description
Espèces réactives
Application
Anti-DRAP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
ChIP
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot