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Merck

GHRL

ghrelin/obestatin prepropeptide

Synonymes:
MTLRP
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(51738) Summary: This gene encodes ghrelin-obestatin preproprotein, which generates ghrelin and obestatin. Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor and is involved in regulating growth hormone release. Obestatin was initially reported to be an endogenous ligand for the orphan G protein-coupled receptor GPR39 and was involved in satiety and decreased food intake; however, these findings are controversial. Recent reports show that obestatin is involved in inhibiting thirst and anxiety, improving memory, regulating sleep, affecting cell proliferation, and increasing the secretion of pancreatic juice enzymes. Alternative promoters and alternative splicing result in multiple transcript variants, some of which encode different protein isoforms and some of which do not encode a protein but may regulate the ghrelin-obestatin preproprotein expression. In addition, antisense transcripts for this gene have been identified and may also function in regulation of the ghrelin-obestatin preproprotein expression. [provided by RefSeq, Oct 2008]
  • Mouse(58991) ghrelin
  • Rat(59301) ghrelin/obestatin prepropeptide
  • Zebrafish(798613) ghrelin/obestatin preprohormone
  • chicken(408185) ghrelin/obestatin prepropeptide
  • naked mole-rat(101710248) ghrelin/obestatin prepropeptide
  • Horse(100058008) ghrelin/obestatin prepropeptide
  • domestic guinea pig(100717245) ghrelin/obestatin prepropeptide
  • sheep(442996) ghrelin/obestatin prepropeptide
  • Goat(100861189) ghrelin/obestatin prepropeptide
  • dog(403587) ghrelin/obestatin prepropeptide
  • domestic cat(493844) ghrelin/obestatin prepropeptide
  • cow(281192) ghrelin/obestatin prepropeptide

Custom & Knockdown Gene Products

ELISA

Numéro du produit
Description
Espèce(s)
Obestatin EIA Kit, for serum, plasma, culture supernatant and cell lysates,
Espèce(s)
human

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-Ghrelin Antibody, clone 1ML-1D7, ascites fluid, clone 1ML-1D7, from mouse,
Espèces réactives
human, mouse
Application
immunocytochemistry
western blot
Anti-GHRL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Monoclonal Anti-GHRL antibody produced in mouse, clone 4B8, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunohistochemistry

western blot
Anti-Obestatin Antibody, Chemicon®, from chicken,
Espèces réactives
mouse, rat
Application
ELISA

Proteins

Numéro du produit
Description
Espèce(s)
Ghrelin rat, lyophilized powder,
Espèce(s)
rat