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Merck

GPC3

glypican 3

Synonymes:
DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(2719) Summary: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
  • Mouse(14734) glypican 3
  • Rat(25236) glypican 3
  • Zebrafish(387365) glypican 3
  • domestic guinea pig(100726246) glypican 3
  • chicken(770863) glypican 3
  • Domestic Rabbit(100351858) glypican 3
  • sheep(101119285) glypican 3
  • cow(615239) glypican 3
  • domestic cat(101094739) glypican 3
  • dog(481056) glypican 3

Custom & Knockdown Gene Products

ELISA

Numéro du produit
Description
Espèce(s)
Human Glypican 3 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Espèce(s)
human

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Glypican-3 (1G12), ,
Espèces réactives
human
Application
immunohistochemistry
Anti-GPC3 Antibody, clone 9C2, ascites fluid, clone 9C2, from mouse,
Espèces réactives
human, mouse
Application
flow cytometry
immunofluorescence

immunohistochemistry

western blot
Anti-Glypican-3 antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP86, affinity isolated antibody,
Espèces réactives
human
Application
flow cytometry
immunohistochemistry

western blot
Anti-GPC3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-GPC3, IgG fraction of antiserum,
Espèces réactives
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot

Proteins

Numéro du produit
Description
Espèce(s)
Glypican 3, recombinant, expressed in NSO cells,
Espèce(s)
human
Monkey (M. fascicularis) GPC3, His-Tag, recombinant, expressed in HEK 293 cells,
Espèce(s)
mouse

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human GPC3,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Gpc3,
Espèce(s)
mouse