GRM6
glutamate receptor, metabotropic 6
Synonymes:
CSNB1B, GPRC1F, MGLUR6, mGlu6
Espèce(s):
Human GRM6 (2916), Mouse Grm6 (108072), Rat Grm6 (24419), domestic guinea pig Grm6 (100722389), naked mole-rat Grm6 (101717017), cow GRM6 (529656), domestic cat GRM6 (101097449), dog GRM6 (481452)
ID UniProtKB:
ID du gène:
- Human(2916) Summary: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. [provided by RefSeq, Feb 2012]
- Mouse(108072) glutamate receptor, metabotropic 6
- Rat(24419) glutamate receptor, metabotropic 6
- domestic guinea pig(100722389) glutamate receptor, metabotropic 6
- naked mole-rat(101717017) glutamate receptor, metabotropic 6
- cow(529656) glutamate receptor, metabotropic 6
- domestic cat(101097449) glutamate receptor, metabotropic 6
- dog(481452) glutamate receptor, metabotropic 6
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Small Molecule - Agonist
Numéro du produit
Description
Espèce(s)
L-(+)-2-Amino-4-phosphonobutyric acid, optical purity optical purity: ≥95% (HPLC, Marfey′s reagent),
Espèce(s)
rat, human
Small Molecule - Antagonist
Numéro du produit
Description
Espèce(s)
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Espèce(s)
rat, human
Antibodies
Numéro du produit
Description
Espèces réactives
Application
Anti-MGLUR6 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-GRM6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunohistochemistry
Small Molecule - Mixed Agonist/Antagonist
Numéro du produit
Description
Espèce(s)
L-(+)-2-Amino-4-phosphonobutyric acid, optical purity optical purity: ≥95% (HPLC, Marfey′s reagent),
Espèce(s)
rat, human
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Espèce(s)
rat, human