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Merck

HBA2

hemoglobin, alpha 2

Synonymes:
HBH
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(3040) Summary: The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported. [provided by RefSeq, Jul 2008]
  • Rat(360504) hemoglobin, alpha 2
  • Horse(100036558) hemoglobin, alpha 2

Custom & Knockdown Gene Products

Small Molecule - Allosteric Modulator

Numéro du produit
Description
Espèce(s)
Bezafibrate, ≥98%, solid,
Espèce(s)
mouse, human

Small Molecule - Antagonist

Numéro du produit
Description
Espèce(s)
3-(Diethylamino)propyl isothiocyanate, 97%,
Espèce(s)
human

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-Haemoglobin Alpha Chain antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP212, affinity isolated antibody,
Espèces réactives
human
Application
flow cytometry
immunohistochemistry

western blot
ANTI-HBA2 (CENTER) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Espèces réactives
human, mouse
Application
flow cytometry
immunohistochemistry

western blot

Kits

Numéro du produit
Description
Espèce(s)
Hemoglobin Assay Kit, sufficient for 250 colorimetric tests,
Espèce(s)
mouse, rat, human

Proteins

Numéro du produit
Description
Espèce(s)
Hemoglobin A2, Ferrous Stabilized human, lyophilized powder,
Espèce(s)
human
Hemoglobin human, lyophilized powder,
Espèce(s)
human

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human HBA2, HBA1,
Espèce(s)
human