HP
haptoglobin
Synonymes:
BP, HP2ALPHA2, HPA1S
Espèce(s):
Human HP (3240), Mouse Hp (15439), Rat Hp (24464), Zebrafish hp (566096), fruit fly hp (251278), domestic cat HP (100144610), dog HP (479668), Domestic Rabbit HP (100008816), sheep HP (101102413), cow HP (280692) ...Plus
ID UniProtKB:
ID du gène:
- Human(3240) Summary: This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(15439) haptoglobin
- Rat(24464) haptoglobin
- Zebrafish(566096) haptoglobin
- fruit fly(251278) humped
- domestic cat(100144610) haptoglobin
- dog(479668) haptoglobin
- Domestic Rabbit(100008816) haptoglobin
- sheep(101102413) haptoglobin
- cow(280692) haptoglobin
- naked mole-rat(101705743) haptoglobin
- domestic guinea pig(100721435) haptoglobin
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Antibodies
Numéro du produit
Description
Espèces réactives
Application
Anti-Haptoglobin antibody produced in rabbit, IgG fraction of antiserum, lyophilized powder,
Espèces réactives
human
Application
ELISA
Anti-Haptoglobin antibody, Mouse monoclonal, clone HG-36, purified from hybridoma cell culture,
Espèces réactives
human
Application
ELISA
dot blot
immunoprecipitation (IP)
western blot
dot blot
immunoprecipitation (IP)
western blot
Monoclonal Anti-Haptoglobin antibody produced in mouse, clone HG-36, ascites fluid,
Espèces réactives
human
Application
ELISA
Anti-Haptoglobin (HP) antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-Haptoglobin Antibody, clone P2A12, ,
Espèces réactives
human
Application
immunohistochemistry
western blot
western blot
Proteins
esiRNA
Numéro du produit
Description
Espèce(s)