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Merck

ITGAM

integrin, alpha M (complement component 3 receptor 3 subunit)

Synonymes:
CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(3684) Summary: This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
  • Mouse(16409) integrin alpha M
  • Rat(25021) integrin, alpha M
  • Horse(100064803) integrin, alpha M (complement component 3 receptor 3 subunit)
  • dog(489928) integrin, alpha M (complement component 3 receptor 3 subunit)
  • sheep(443217) integrin, alpha M (complement component 3 receptor 3 subunit)
  • domestic guinea pig(100135561) integrin, alpha M (complement component 3 receptor 3 subunit)
  • domestic cat(101087957) integrin, alpha M (complement component 3 receptor 3 subunit)
  • cow(407124) integrin, alpha M (complement component 3 receptor 3 subunit)
  • naked mole-rat(101719288) integrin, alpha M (complement component 3 receptor 3 subunit)
  • Domestic Rabbit(100351865) integrin, alpha M (complement component 3 receptor 3 subunit)

Custom & Knockdown Gene Products

ELISA

Numéro du produit
Description
Espèce(s)
Human Integrin alpha-M ELISA, for serum, plasma and cell culture supernatants,
Espèce(s)
human

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-Integrin αM [CD11b] Antibody, clone OX-42, clone OX-42, Chemicon®, from mouse,
Espèces réactives
rat
Application
flow cytometry
immunohistochemistry

immunoprecipitation (IP)
®, clone 2LPM19c, Milli-Mark®, from mouse,
Espèces réactives
human
Application
flow cytometry
Anti-Integrin αM [CD11b] Antibody, clone OX-42, FITC conjugated, clone OX-42, Chemicon®, from mouse,
Espèces réactives
rat
Application
flow cytometry
immunohistochemistry
Anti-CD11b/CD18 Antibody, clone mAb107, clone mAb107, from mouse,
Espèces réactives
human, nonhuman primates
Application
dot blot
flow cytometry

immunohistochemistry

inhibition assay
Monoclonal Anti-CD11b antibody produced in mouse, clone ICRF44, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
flow cytometry

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human ITGAM,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Itgam,
Espèce(s)
mouse