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Merck

MANEA

mannosidase, endo-alpha

Synonymes:
ENDO, hEndo
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(79694) Summary: N-glycosylation of proteins is initiated in the endoplasmic reticulum (ER) by the transfer of the preassembled oligosaccharide glucose-3-mannose-9-N-acetylglucosamine-2 from dolichyl pyrophosphate to acceptor sites on the target protein by an oligosaccharyltransferase complex. This core oligosaccharide is sequentially processed by several ER glycosidases and by an endomannosidase (E.C. 3.2.1.130), such as MANEA, in the Golgi. MANEA catalyzes the release of mono-, di-, and triglucosylmannose oligosaccharides by cleaving the alpha-1,2-mannosidic bond that links them to high-mannose glycans (Hamilton et al., 2005 [PubMed 15677381]
  • Mouse(242362) mannosidase, endo-alpha
  • Rat(140808) mannosidase, endo-alpha
  • domestic guinea pig(100718937) mannosidase, endo-alpha
  • dog(481925) mannosidase, endo-alpha
  • chicken(421807) mannosidase, endo-alpha
  • Zebrafish(447827) mannosidase, endo-alpha
  • sheep(101106778) mannosidase, endo-alpha
  • cow(512853) mannosidase, endo-alpha
  • Horse(100065922) mannosidase, endo-alpha
  • domestic cat(101101567) mannosidase, endo-alpha
  • naked mole-rat(101724745) mannosidase, endo-alpha

Custom & Knockdown Gene Products

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-MANEA antibody produced in rabbit, Ab2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-MANEA antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human MANEA,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Manea,
Espèce(s)
mouse