MAP2K1
mitogen-activated protein kinase kinase 1
Synonymes:
CFC3, MAPKK1, MEK1, MKK1, PRKMK1
Espèce(s):
Human MAP2K1 (5604), Mouse Map2k1 (26395), Rat Map2k1 (170851), domestic guinea pig Map2k1 (100712888), dog MAP2K1 (478347), Horse MAP2K1 (100065996), domestic cat MAP2K1 (101081387), chicken MAP2K1 (415549), naked mole-rat Map2k1 (101715628), cow MAP2K1 (533199) ...Plus
ID UniProtKB:
ID du gène:
- Human(5604) Summary: The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq, Jul 2008]
- Mouse(26395) mitogen-activated protein kinase kinase 1
- Rat(170851) mitogen activated protein kinase kinase 1
- domestic guinea pig(100712888) mitogen-activated protein kinase kinase 1
- dog(478347) mitogen-activated protein kinase kinase 1
- Horse(100065996) mitogen-activated protein kinase kinase 1
- domestic cat(101081387) mitogen-activated protein kinase kinase 1
- chicken(415549) mitogen-activated protein kinase kinase 1
- naked mole-rat(101715628) mitogen-activated protein kinase kinase 1
- cow(533199) mitogen-activated protein kinase kinase 1
- Domestic Rabbit(100009316) mitogen-activated protein kinase kinase 1
- sheep(101123635) mitogen-activated protein kinase kinase 1
- Zebrafish(406728) mitogen-activated protein kinase kinase 1
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ELISA
Numéro du produit
Description
Espèce(s)
Phospho-Mek (pSer217 / 221) ELISA Kit, for detection of phospho-mek (pSer217 / 221) in human, mouse or rat cell and tissue lysates,
Espèce(s)
human
Phospho-Mek (pSer217 / 221) and pan-Mek ELISA Kit, for detection of phospho-mek (pSer217 / 221) and pan-mek in human, mouse or rat cell and tissue lysates,
Espèce(s)
human
Antibodies
Numéro du produit
Description
Espèces réactives
Application
Anti-MEK1 Antibody, Upstate®, from rabbit,
Espèces réactives
human, mouse, rat
Application
immunoprecipitation (IP)
western blot
western blot
Anti-phospho-MEK1 (Ser218/222)/MEK2 (Ser222/226) Antibody, rabbit monoclonal, Upstate®, from rabbit,
Espèces réactives
human, mouse, rat
Application
western blot
Anti-phospho-MEK1 (Thr292) Antibody, Upstate®, from rabbit,
Espèces réactives
human, mouse
Application
western blot
Anti-MEK1 Antibody, clone 6B7.1, clone 6B7.1, from mouse,
Espèces réactives
human
Application
western blot
Anti-MAP2K1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
Numéro du produit
Description
Espèce(s)
U0126, U0126 is a elective inhibitor of MEK-1 and MEK-2; weak inhibitor of PKC, Raf, ERK, JNK, MEKK, MKK-3, MKK-4/SEK, MKK-6, Abl, Cdk2 and Cdk4.,
Espèce(s)
human
Proteins
Numéro du produit
Description
Espèce(s)
MEK1 Protein, inactive, 50 g, Unactive, N-terminal GST & C-terminal His6-tagged, recombinant full-length human MEK1, for use in Kinase Assays.,
Espèce(s)
human
MEK1 Protein, active, 10 µg, Active, N-terminal GST & C-terminal His6-tagged, recombinant full-length human MEK1, for use in Kinase Assays.,
Espèce(s)
human
MEK1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
mouse