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Merck

MAX

MYC associated factor X

Synonymes:
bHLHd4
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(4149) Summary: The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
  • Mouse(17187) Max protein
  • Rat(60661) MYC associated factor X
  • fruit fly(40095) CG9648 gene product from transcript CG9648-RA
  • Zebrafish(30467) myc-associated factor X
  • chicken(100858676) MYC associated factor X
  • dog(609969) MYC associated factor X
  • domestic cat(493947) MYC associated factor X
  • cow(540616) MYC associated factor X
  • domestic guinea pig(100718960) MYC associated factor X
  • naked mole-rat(101699034) MYC associated factor X

Custom & Knockdown Gene Products

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Monoclonal Anti-MAX antibody produced in mouse, clone 4E10-1A9, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunofluorescence

proximity ligation assay

western blot
Anti-MAX antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
ChIP
immunohistochemistry
Anti-MAX antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry
Anti-Phospho-MAX-S11 antibody produced in rabbit, ,
Espèces réactives
human
Application
immunofluorescence
western blot
Anti-MAX antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, pig, rat
Application
western blot

Proteins

Numéro du produit
Description
Espèce(s)
Myc-associated factor X (MAX) human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Espèce(s)
human

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Max,
Espèce(s)
mouse
MISSION® esiRNA, targeting human MAX,
Espèce(s)
human