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Merck

PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

Synonymes:
PAK5
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(56924) Summary: This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
  • Mouse(214230) p21 protein (Cdc42/Rac)-activated kinase 6
  • Rat(296078) p21 protein (Cdc42/Rac)-activated kinase 6
  • domestic guinea pig(100713585) p21 protein (Cdc42/Rac)-activated kinase 6
  • naked mole-rat(101706200) p21 protein (Cdc42/Rac)-activated kinase 6
  • chicken(428837) p21 protein (Cdc42/Rac)-activated kinase 6
  • Domestic Rabbit(100348921) p21 protein (Cdc42/Rac)-activated kinase 6
  • dog(487490) p21 protein (Cdc42/Rac)-activated kinase 6
  • domestic cat(101091201) p21 protein (Cdc42/Rac)-activated kinase 6
  • Horse(100071463) p21 protein (Cdc42/Rac)-activated kinase 6
  • cow(539224) p21 protein (Cdc42/Rac)-activated kinase 6
  • Goat(100860973) p21 protein (Cdc42/Rac)-activated kinase 6
  • sheep(101112573) p21 protein (Cdc42/Rac)-activated kinase 6

Custom & Knockdown Gene Products

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-PAK6 (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, canine, goat, guinea pig, horse, human, mouse, rabbit
Application
western blot
Anti-phospho-PAK5/6 (pSer602/560) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
western blot
Anti-Phospho-PAK4/PAK5/PAK6-S474/S560/S602 antibody produced in rabbit, ,
Espèces réactives
human, mouse
Application
western blot
Anti-phospho-PAK4 /PAK5 /PAK6 (Ser474 /Ser560/ Ser602) Antibody, clone 24GB445, Rabbit Monoclonal, clone 24GB445, recombinant rabbit monoclonal, expressed in HEK293 cells,
Espèces réactives
human, rat
Application
flow cytometry
immunofluorescence

western blot

Proteins

Numéro du produit
Description
Espèce(s)
PAK6, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human PAK6, BUB1B-PAK6,
Espèce(s)
human