PRCP
prolylcarboxypeptidase (angiotensinase C)
Synonymes:
HUMPCP, PCP
Espèce(s):
Human PRCP (5547), Mouse Prcp (72461), Rat Prcp (293118), sheep PRCP (101107644), Horse PRCP (100061830), domestic cat PRCP (101100665), cow PRCP (534927), naked mole-rat Prcp (101719590), chicken PRCP (428096), dog PRCP (476788) ...Plus
ID UniProtKB:
ID du gène:
- Human(5547) Summary: The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
- Mouse(72461) prolylcarboxypeptidase (angiotensinase C)
- Rat(293118) prolylcarboxypeptidase (angiotensinase C)
- sheep(101107644) prolylcarboxypeptidase (angiotensinase C)
- Horse(100061830) prolylcarboxypeptidase (angiotensinase C)
- domestic cat(101100665) prolylcarboxypeptidase (angiotensinase C)
- cow(534927) prolylcarboxypeptidase (angiotensinase C)
- naked mole-rat(101719590) prolylcarboxypeptidase (angiotensinase C)
- chicken(428096) prolylcarboxypeptidase (angiotensinase C)
- dog(476788) prolylcarboxypeptidase (angiotensinase C)
- Zebrafish(436967) prolylcarboxypeptidase (angiotensinase C)
- domestic guinea pig(100734342) prolylcarboxypeptidase (angiotensinase C)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Numéro du produit
Description
Espèce(s)
Antibodies
Numéro du produit
Description
Espèces réactives
Application
Anti-PRCP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
western blot
Anti-PRCP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
western blot
western blot
Proteins
Numéro du produit
Description
Espèce(s)
PrCP active human, recombinant, expressed in FreeStyle™ 293-F cells, ≥15% (SDS-PAGE),
Espèce(s)
human