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Merck

PYCARD

PYD and CARD domain containing

Synonymes:
ASC, CARD5, TMS, TMS-1, TMS1
Espèce(s):
Human PYCARD (29108), Mouse Pycard (66824), Rat Pycard (282817), Goat PYCARD (100861338), domestic guinea pig Pycard (100734858), domestic cat PYCARD (101088449), sheep PYCARD (101105208), dog PYCARD (489925), Zebrafish pycard (57923), cow PYCARD (282846)
ID UniProtKB:
Q9ULZ3, Q96D12, Q9BSZ5, Q9HBD0, Q9NXJ8
ID du gène:
  • Human(29108) Summary: This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(66824) PYD and CARD domain containing
  • Rat(282817) PYD and CARD domain containing
  • Goat(100861338) PYD and CARD domain containing
  • domestic guinea pig(100734858) PYD and CARD domain containing
  • domestic cat(101088449) PYD and CARD domain containing
  • sheep(101105208) PYD and CARD domain containing
  • dog(489925) PYD and CARD domain containing
  • Zebrafish(57923) PYD and CARD domain containing
  • cow(282846) PYD and CARD domain containing

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Antibodies

Numéro du produit
Description
Espèces réactives
Application
04-147
Anticorps anti-ASC, clone 2EI-7, clone 2EI-7, from mouse,
Espèces réactives
human, mouse
Application
flow cytometry
western blot
SAB4501315
Anti-ASC antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
SAB5700702
Anti-ASC/TMS1 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
western blot
HPA054496
Anti-PYCARD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
PRS2287
Anti-ASC antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunocytochemistry
immunohistochemistry
western blot

esiRNA

Numéro du produit
Description
Espèce(s)
EHU066851
MISSION® esiRNA, targeting human PYCARD,
Espèce(s)
human