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Merck

RGR

retinal G protein coupled receptor

Synonymes:
RP44
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(5995) Summary: This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(57811) retinal G protein coupled receptor
  • Rat(306307) retinal G protein coupled receptor
  • fruit fly(35843) regular
  • chicken(423619) retinal G protein coupled receptor
  • dog(489072) retinal G protein coupled receptor
  • domestic cat(101083036) retinal G protein coupled receptor
  • sheep(101110564) retinal G protein coupled receptor
  • cow(280911) retinal G protein coupled receptor
  • naked mole-rat(101705893) retinal G protein coupled receptor
  • domestic guinea pig(100725184) retinal G protein coupled receptor

Custom & Knockdown Gene Products

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-Rgr antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Espèces réactives
human
Application
immunofluorescence
western blot
Anti-Rgr Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human RGR,
Espèce(s)
human