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Merck

SRF

serum response factor (c-fos serum response element-binding transcription factor)

Synonymes:
MCM1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(6722) Summary: This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). [provided by RefSeq, Jul 2008]
  • Mouse(20807) serum response factor
  • Rat(501099) serum response factor (c-fos serum response element-binding transcription factor)
  • fruit fly(252723) Surf wings
  • chicken(396103) serum response factor (c-fos serum response element-binding transcription factor)
  • domestic cat(101085210) serum response factor (c-fos serum response element-binding transcription factor)
  • dog(612861) serum response factor (c-fos serum response element-binding transcription factor)
  • cow(533039) serum response factor (c-fos serum response element-binding transcription factor)
  • sheep(101111402) serum response factor (c-fos serum response element-binding transcription factor)
  • domestic guinea pig(100715998) serum response factor (c-fos serum response element-binding transcription factor)
  • naked mole-rat(101719000) serum response factor (c-fos serum response element-binding transcription factor)

Custom & Knockdown Gene Products

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-SRF Antibody, clone 1H14 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry

western blot
Anti-SRF antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-SRF Antibody, clone 2C5, ,
Espèces réactives
human, mouse
Application
immunohistochemistry
Anti-Phospho-SRF-S103 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-SRF antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot

Proteins

Numéro du produit
Description
Espèce(s)
C-fos, proto oncogene human, recombinant, expressed in insect cells, ≥70% (SDS-PAGE),
Espèce(s)
human

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human SRF,
Espèce(s)
human