TYK2
tyrosine kinase 2
Synonymes:
JTK1
Espèce(s):
Human TYK2 (7297), Mouse Tyk2 (54721), Rat Tyk2 (100361294), domestic cat TYK2 (101090171), dog TYK2 (476714), chicken TYK2 (430113), Zebrafish tyk2 (100536675), cow TYK2 (512484), domestic guinea pig Tyk2 (100715734), sheep TYK2 (101117248)
ID UniProtKB:
ID du gène:
- Human(7297) Summary: This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008]
- Mouse(54721) tyrosine kinase 2
- Rat(100361294) tyrosine kinase 2
- domestic cat(101090171) tyrosine kinase 2
- dog(476714) tyrosine kinase 2
- chicken(430113) tyrosine kinase 2
- Zebrafish(100536675) tyrosine kinase 2
- cow(512484) tyrosine kinase 2
- domestic guinea pig(100715734) tyrosine kinase 2
- sheep(101117248) tyrosine kinase 2
- naked mole-rat(101715782) tyrosine kinase 2
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ELISA
Numéro du produit
Description
Espèce(s)
Antibodies
Numéro du produit
Description
Espèces réactives
Application
Anti-TYK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-TYK2 Antibody, clone 2H22 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
bovine, human, monkey, porcine
Application
affinity binding assay
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Phospho-Tyk2-Y1054/1055 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-phospho-TYK2 (pTyr1054) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
western blot
Anti-phospho-Tyk2 (pTyr1054/1055) antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
western blot
Small Molecule - Inhibitor
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Description
Espèce(s)
esiRNA
Numéro du produit
Description
Espèce(s)