WT1
Wilms tumor 1
Synonymes:
AWT1, EWS-WT1, GUD, NPHS4, WAGR, WIT-2, WT33
Espèce(s):
Human WT1 (7490), Mouse Wt1 (22431), Rat Wt1 (24883), domestic guinea pig Wt1 (100716139), dog WT1 (609253), sheep WT1 (100101227), naked mole-rat Wt1 (101714640), cow WT1 (280959), chicken WT1 (396139), cow WT1 (782183) ...Plus
ID UniProtKB:
ID du gène:
- Human(7490) Summary: This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation site upstream of and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq, Oct 2010]
- Mouse(22431) Wilms tumor 1 homolog
- Rat(24883) Wilms tumor 1
- domestic guinea pig(100716139) Wilms tumor 1
- dog(609253) Wilms tumor 1
- sheep(100101227) Wilms tumor 1
- naked mole-rat(101714640) Wilms tumor 1
- cow(280959) Wilms tumor 1
- chicken(396139) Wilms tumor 1
- cow(782183) Wilms tumor 1
- cow(614584) Wilms tumor 1
- domestic cat(101088518) Wilms tumor 1
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Antibodies
Numéro du produit
Description
Espèces réactives
Application
WT1 (6F-H2) Mouse Monoclonal Antibody, ,
Espèces réactives
human
Application
immunohistochemistry
Anti-WT1 Antibody, clone 6F-H2, clone 6F-H2, Upstate®, from mouse,
Espèces réactives
human
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anticorps anti-tumeur de Wilms (NT), clone 6F-H2, clone 6F-H2, Chemicon®, from mouse,
Espèces réactives
human, mouse
Application
immunocytochemistry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-WT1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
western blot
Monoclonal Anti-WT1 antibody produced in mouse, clone 1E9, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
esiRNA
Numéro du produit
Description
Espèce(s)