Merck
All Photos(1)

581500

Sigma-Aldrich

TEMPOL - CAS 2226-96-2 - Calbiochem

A stable, cell-permeable nitroxide that acts as a free radical scavenger and nitric oxide spin trap.

Synonym(s):
TEMPOL - CAS 2226-96-2 - Calbiochem, 4-Hydroxy-TEMPO, 4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl
Empirical Formula (Hill Notation):
C9H18NO2
CAS Number:
Molecular Weight:
172.24
Numéro MDL:

Niveau de qualité

100

Essai/Dosage

≥97% total nitrogen (N) basis

Forme

crystals
powder

manufacturer/tradename

Calbiochem®

Conditions de stockage

OK to freeze
protect from light

Couleur

orange

Solubilité

DMSO: 5 mg/mL
ethanol: soluble
water: soluble

Expédié(e)(s) dans

ambient

Temp. de stockage

−20°C

InChI

1S/C9H18NO2/c1-8(2)5-7(11)6-9(3,4)10(8)12/h7,11H,5-6H2,1-4H3

InChI key

UZFMOKQJFYMBGY-UHFFFAOYSA-N

Description générale

A stable, cell-permeable nitroxide that acts as a free radical scavenger and nitric oxide spin trap. Induces oxidative stress and enhances the levels of p21WAF1 in HL-60 cells in a dose-dependent manner. Reported to reduce organ injury following hemorrhagic shock. Exhibits radio-protective and anti-proliferative properties.
A stable, cell-permeable nitroxide free radical that acts as a radical scavenger and nitric oxide spin trap. Induces oxidative stress and enhances the levels of p21WAF1 in HL-60 cells in a dose-dependent manner. Reported to reduce organ injury following hemorrhagic shock. Exhibits radio-protective and anti-proliferative properties.

Conditionnement

500 mg in Plastic ampoule
Packaged under inert gas

Actions biochimiques/physiologiques

Cell permeable: yes
Product does not compete with ATP.
Reversible: no
Primary Target
Free radical scavenger and nitric oxide spin trap

Avertissement

Toxicity: Harmful (C)

Reconstitution

Prepare fresh solutions. Following reconstitution, aliquot and freeze (-20°C).

Autres remarques

Gariboldi, M.B., et al. 2000. Free Radic. Biol. Med.29, 633.
Miura, Y., et al. 2000. J. Radiat. Res. (Tokyo)41, 103.
Mota-Filipe, H., et al. 1999. Shock 12, 255.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

CorrosionExclamation mark

Mention d'avertissement

Danger

Mentions de danger

Classification des risques

Acute Tox. 4 Oral - Eye Dam. 1

Code de la classe de stockage

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

294.8 °F - DIN 51758

Point d'éclair C

146 °C - DIN 51758

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Quality

Enter Lot Number to search for Certificate of Quality (COQ).

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service