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AB19013

Sigma-Aldrich

Anti-Tenascin Antibody

Chemicon®, from rabbit

eCl@ss:
32160702
NACRES:
NA.41

Source biologique

rabbit

Niveau de qualité

100

Forme d'anticorps

affinity isolated antibody

antibody product type

primary antibodies

Clone

polyclonal

Purifié(e)(s) par

affinity chromatography

species reactivity

chicken, human

manufacturer/tradename

Chemicon®

Application(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable

N° d'accession NCBI

N° d'accession UniProt

Expédié(e)(s) dans

dry ice

Spécificité

Reactive with tenascin from chicken and human by immunohistochemistry. Under reducing conditions, reactivity to chicken is approximately 100X greater than reactivity with human tenascin. Reactivity with mouse tenascin under reducing conditions is poor, but reacts with mouse in paraffin embedded sections.

Immunogène

Purified tenascin from embryonic chicken brain.

Application

Research Category
Cell Structure
Anti-Tenascin Antibody is an antibody against Tenascin for use in IH, IH(P).
Function blocking

Western blot: Antibody recognizes a 220-240kDa band in reduced westerns; antibody reacts best with chicken, followed by human (100X less reactive). Mouse reactivity under reduced conditions is poor.

Immunohistochemistry: frozen and paraffin embedded tissues; citrate treatment useful for paraffin tissues.

Optimal working dilutions must be determined by the end user.
Research Sub Category
ECM Proteins

Liaison

Replaces: AB1951

Forme physique

ImmunoAffinity Purified
Affinity Purified using immobilized chicken tenascin. Provided as a liquid in PBS, containing no preservatives.

Stockage et stabilité

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Remarque sur l'analyse

Control
Embryonic chicken brain

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

12 - Non Combustible Liquids

WGK Allemagne

WGK 2

Flash Point(F)

Not applicable

Point d'éclair C

Not applicable

Certificat d'analyse

Certificat d'origine

Fluorescent whole-mount method for visualizing three-dimensional relationships in intact and regenerating adult newt spinal cords.
Zukor, KA; Kent, DT; Odelberg, SJ
Developmental Dynamics null
Ashley W Seifert et al.
PloS one, 7(4), e32875-e32875 (2012-04-10)
While considerable progress has been made towards understanding the complex processes and pathways that regulate human wound healing, regenerative medicine has been unable to develop therapies that coax the natural wound environment to heal scar-free. The inability to induce perfect...
Sarah Calve et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 26(6), 2538-2545 (2012-03-15)
During forelimb regeneration in the newt Notophthalmus viridescens, the dynamic expression of a transitional matrix rich in hyaluronic acid, tenascin-C, and fibronectin controls muscle cell behavior in vivo and in vitro. However, the influence of extracellular matrix (ECM) remodeling on...
Guoqiang Wan et al.
Frontiers in aging neuroscience, 11, 156-156 (2019-07-12)
Age-related decline of inner ear function contributes to both hearing loss and balance disorders, which lead to impaired quality of life and falls that can result in injury and even death. The cellular mechanisms responsible for the ear's functional decline...
Katherine A Zukor et al.
Neural development, 6, 1-1 (2011-01-06)
Newts have the remarkable ability to regenerate their spinal cords as adults. Their spinal cords regenerate with the regenerating tail after tail amputation, as well as after a gap-inducing spinal cord injury (SCI), such as a complete transection. While most...

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