MABC531

Sigma-Aldrich

Anti-Somatotropin/GH1 Antibody, clone 1H1.1

clone 1H1.1, from mouse

Synonyme(s):
Somatotropin, Growth hormone, GH, GH-N, Growth hormone 1, Pituitary growth hormone, -Somatotropin/GH1
eCl@ss:
32160702

Niveau de qualité

100

Source biologique

mouse

antibody product type

primary antibodies

Clone

1H1.1, monoclonal

species reactivity

human

Application(s)

western blot: suitable

Isotype

IgG1κ

N° d'accession NCBI

N° d'accession UniProt

Expédié(e)(s) dans

wet ice

Gene Information

human ... GH1(2688)

Description générale

Somatotropin (UniProt P01241; also known as GH, GH-N, Growth hormone 1, hGH-N, Pituitary growth hormone) is encoded by the GH1 (also known as GH, GHN, IGHD1B) gene (Gene ID 8856) in human. Somatotropin is a peptide hormone that plays an important role in growth control by inducing IGF-1 secretion in liver and other tissues. It stimulates myoblast differentiation and proliferation, as well as amino acids uptake and protein synthesis in muscle and other tissues. Acromegaly is a rare endocrine syndrome caused by a GH-secreting pituitary adenoma. Acromegaly may also be rarely associated with a hypothalamic or an ectopic GH-releasing hormone-producing tumor.

Spécificité

Expected to react with isoforms 1, 3, and 4. Reactivity to isoforms 2 and 5 have not been tested.

Immunogène

GST-tagged recombinant protein corresponding to human Somatotropin/GH1.

Application

Research Sub Category
Apoptosis - Additional
Anti-Somatotropin/GH1 Antibody, clone 1H1.1 is an antibody against Somatotropin/GH1 for use in Western Blotting.
Research Category
Apoptosis & Cancer

Qualité

Evaluated by Western Blotting in human pituitary tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected Somatotropin/GH1 in 10 µg of human pituitary tissue lysate.

Description de la cible

~25 kDa observed. This protein has several isoforms from ~20-25 kDa

Forme physique

Protein G Purified
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Autres remarques

Concentration: Please refer to lot specific datasheet.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK Allemagne

WGK 1

Flash Point(F)

Not applicable

Point d'éclair C

Not applicable

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