MABF301

Sigma-Aldrich

Anti-Interleukin-7/IL-7 Antibody, clone 7B1.1

clone 7B1.1, from mouse

Synonyme(s):
Interleukin-7, IL-7
eCl@ss:
32160702
NACRES:
NA.41

Niveau de qualité

100

Source biologique

mouse

antibody product type

primary antibodies

Clone

7B1.1, monoclonal

species reactivity

human

Application(s)

flow cytometry: suitable
western blot: suitable

Isotype

IgG2aκ

N° d'accession NCBI

N° d'accession UniProt

Expédié(e)(s) dans

wet ice

Gene Information

human ... IL7(3574)

Description générale

The protein named IL-7, or interleukin 7 is a hematopoietic growth factor secreted by stromal cell in the bone marrow and thymus but also produced by many other cell types including keratinocytes, epithelial cells, hepatocytes and macrophage/dendritic cells but not by classical lymphocytes. IL7 is a cytokine that has multiple functions and is critical for proper T cell maturation and lymphoid cell survival, and its expression stimulates the proliferation of B cells, T cell and NK cells. IL-7 is detected by cells via its receptor and binding results in a cascade of signals important for T cell development and for T cell survival within the periphery, as well as memory T cells. IL-7 expression is upregulated in various lymphomas and leukemias and because of its effects on T cell development IL-7 is being examined as a therapeutic agent for transplantation studies and even latent viral infection studies.

Immunogène

GST-tagged recombinant protein corresponding to human Interleukin-7/IL-7.

Application

Flow Cytometry Analysis: 1 µg of this antibody detected recombinant Interleukin-7/IL-7 in Jurkat T and Raji B lymphocytes.
This Anti-Interleukin-7/IL-7 Antibody, clone 7B1.1 is validated for use in western blotting & flow cytometry for the detection of Interleukin-7/IL-7.

Qualité

Evaluated by Western Blotting in Interleukin 7 cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected 0.5 µg of recombinant Interleukin-7/IL-7.

Description de la cible

~ 17 kDa observed

Forme physique

Format: Purified

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

WGK Allemagne

WGK 1

Flash Point(F)

Not applicable

Point d'éclair C

Not applicable

Certificat d'analyse
Certificat d'origine

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