MABT200

Sigma-Aldrich

Anti-COL1A2, clone alpha2CT, Azide Free Antibody

clone alpha2CT, from mouse

Synonyme(s):
Annexin A6, 67 kDa calelectrin, Annexin VI, Annexin-6, Calphobindin-II, CPB-II, Lipocortin VI, Protein III, p68, p70
eCl@ss:
32160702
NACRES:
NA.41

Niveau de qualité

100

Source biologique

mouse

antibody product type

primary antibodies

Clone

alpha2CT, monoclonal

species reactivity

human

Application(s)

activity assay: suitable
immunohistochemistry: suitable

Isotype

IgAκ

N° d'accession NCBI

N° d'accession UniProt

Expédié(e)(s) dans

wet ice

Gene Information

human ... ANXA6(309)

Description générale

Collagens are major fibrous structural elements of cartilage, tendon, bone, skin, lung, and blood vessels. Type I collagen, a heterotrimer consisting of two α1 chains and one α2 chain, is the most abundant fibrillar collagen. It is preferentially synthesized in bone, skin, and tendon and is the most abundant protein found in these tissues.

Immunogène

Linear peptide corresponding to the C-terminus of human Collagen type I alpha 2.
Epitope: C-terminus

Application

Research Category
Cell Structure
Activity Assay Analysis: A representative lot from an independent laboratory inhibits fibrin formation in vitro (Chung, H. J., et al. (2008). J Biol Chem. 283(38):25879-25886.).
Anti-COL1A2 antibody, clone alpha2CT, Azide Free is an antibody against COL1A2 for use in IHC & activity assay.
Research Sub Category
Cytoskeleton

Qualité

Evaluated by Immunohistochemistry Analysis in human bone tissues.

Immunohistochemistry Analysis: A 1:50 dilution of this antibody detected COL1A2 in human bone tissues.

Description de la cible

125 and 150 kDa calculated

Forme physique

Purified mouse monoclonal IgAκ in buffer containing PBS without preservatives.
Format: Purified
Protein L

Stockage et stabilité

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK Allemagne

WGK 1

Flash Point(F)

Not applicable

Point d'éclair C

Not applicable

Collagen fibril formation. A new target to limit fibrosis.
Chung, Hye Jin, et al.
The Journal of Biological Chemistry, 283, 25879-25886 (2008)

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