SKBM02560

Millipore

Strat-M® Membrane, Transdermal Diffusion Test Model, 25mm

Strat-M membrane is a synthetic, non-animal based model for transdermal diffusion testing that is predictive of diffusion in human skin without lot-to-lot variability, safety & storage limitations.

eCl@ss:
32160907
NACRES:
NB.24

Matériau

plain filter
polyethersulfone membrane (synthetic lipid post-treatment)
polyolefin membrane (synthetic lipid post-treatment)
white filter

Niveau de qualité

400

Stérilité

non-sterile

manufacturer/tradename

Millipore
Strat-M®

Diam.

2.5 cm

Diam. du filtre

25 mm

Épaisseur

300 μm

Expédié(e)(s) dans

ambient

Description générale

Filter Code: SKBM
Strat-M Membrane for Transdermal Diffusion Testing
Experience the unmatched predictability of Strat-M membrane – a synthetic, non-animal based model for transdermal diffusion testing that is predictive of diffusion in human skin without lot-to-lot variability, safety and storage limitations.

Strat-M membrane is designed for screening of:
•Active pharmaceutical ingredients (API)
•Cosmetic actives
•Formulations
•Personal care products
•Pesticides and chemicals

Human Skin Correlation
Strat-M membrane is predictive of diffusion in human skin for a wide range of compounds and formulations. Use the Compound Correlation Tool to learn how well Strat-M membrane will work for you.

Reproducible Diffusion Data:
No need to repeat testing each time a new lot of skin arrives in the lab. Strat-M membrane is a highly consistent, engineered material that allows you to compare today’s diffusion data with data you will generate next week, or next month. Furthermore, lot-to-lot consistency brings a new level of clarity to your test data, simplifying your analysis.

Sensitive to Enhancers
Strat-M membrane exhibits differential permeability in the presence of enhancers and is compatible with common formulation formats, so it is appropriate for use during formulation optimization.

Ultimate Experimental Convenience
Strat-M membrane was designed with convenience in mind. The Strat-M membrane is shelf-stable and stocked in the warehouse so procurement and storage is a breeze. Each membrane is individually packaged as precut discs and do not need to be hydrated prior to use. Simply remove the Strat-M membrane disc from its pouch and load into a Franz cell.

Application

Strat-M membrane is a synthetic, non-animal based model for transdermal diffusion testing that is predictive of diffusion in human skin without lot-to-lot variability, safety & storage limitations.

Informations légales

STRAT-M is a registered trademark of Merck KGaA, Darmstadt, Germany

Certificat d'analyse

Certificat d'origine

PREDICTION OF SKIN PERMEATION BY CHEMICAL COMPOUNDS USING THE ARTIFICIAL MEMBRANE, STRAT-M?
Uchida T, Kadhum WR, Kanai S, Todo H, Oshizaka T, Sugibayashi K
European Journal of Pharmaceutical Sciences null
IN VITRO SKIN MODELS AS A TOOL IN OPTIMIZATION OF DRUG FORMULATION.
Flaten GE, Palac Z, Engesland A, Filipovic-Grcic J, Vanic Z, Skalko-Basnet N
European Journal of Pharmaceutical Sciences null
IMPACT OF DIFFERENT VEHICLES FOR LASER-ASSISTED DRUG PERMEATION VIA SKIN: FULL-SURFACE VERSUS FRACTIONAL ABLATION.
Lee WR, Shen SC, Aljuffali IA, Li YC, Fang JY.
Pharmaceutical Research null
Membrane properties for permeability testing: Skin versus synthetic membranes
Haq A, Dorrani M, Goodyear B, Joshi V, Michniak-Kohn B.
International Journal of Pharmaceutics null
A REVIEW OF THE CURRENT STATE OF THE ART OF PHYSIOLOGICALLY-BASED TESTS FOR MEASURING HUMAN DERMAL IN VITRO BIOAVAILABILITY OF POLYCYCLIC AROMATIC HYDROCARBONS (PAH) IN SOIL
Beriro DJ, Cave MR, Wragg J, Thomas R, Wills G, Evans F.
Journal of Hazardous Materials null
Articles
Understand how a Strat-M synthetic membrane model can be an alternative to human or animal skin when screening for effectiveness of encapsulation on reducing transdermal diffusion of skin care actives
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