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Merck

79257

Tiliroside

analytical standard

Synonyme(s) :

Astragalin 6"-trans-p-coumarate, Kaempferol 3-O-β-D-(6″-O-(E)-p-coumaroyl)glucopyranoside, Potengriffioside A

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A propos de cet article

Formule empirique (notation de Hill) :
C30H26O13
Numéro CAS:
Poids moléculaire :
594.52
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
85151701
MDL number:
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InChI

1S/C30H26O13/c31-16-6-1-14(2-7-16)3-10-22(35)40-13-21-24(36)26(38)27(39)30(42-21)43-29-25(37)23-19(34)11-18(33)12-20(23)41-28(29)15-4-8-17(32)9-5-15/h1-12,21,24,26-27,30-34,36,38-39H,13H2/b10-3+/t21-,24-,26+,27-,30+/m1/s1

SMILES string

O[C@H]1[C@H](O)[C@@H](COC(=O)\C=C\c2ccc(O)cc2)O[C@@H](OC3=C(Oc4cc(O)cc(O)c4C3=O)c5ccc(O)cc5)[C@@H]1O

InChI key

DVGGLGXQSFURLP-VWMSDXGPSA-N

grade

analytical standard

assay

≥98% (HPLC)

optical activity

[α]/D -65±8°, c = 0.1 in methanol

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

2-8°C

Quality Level

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General description

Tiliroside is a glycosidic flavonoid isolated from Helichrysum italicum. It exhibits a variety of pharmacological properties such as anti-inflammatory, antioxidant, anticarcinogenic and hepatoprotective activity.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Tiliroside may be used as a reference standard in the separation and quantification of tiliroside from plant extracts using solid phase extraction (SPE) followed by reversed-phase high-performance liquid chromatography (RP-HPLC).

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Classe de stockage

11 - Combustible Solids

wgk

WGK 3


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Wei Qiao et al.
Journal of ethnopharmacology, 135(2), 515-521 (2011-04-06)
The present study was carried out to isolate and identify trans-tiliroside as principal compound with anti-hyperglycemic, anti-hyperlipidemic and antioxidant effects from Potentilla chinesis. A bioactive compound, trans-tiliroside was isolated from the ethanol extract of Potentilla chinesis and its administration dose
Nan Qin et al.
European journal of medicinal chemistry, 46(10), 5189-5195 (2011-08-23)
A series of new tiliroside derivatives were synthesized and characterized by analytical (1)H NMR, (13)C NMR and mass spectrometry. All of the compounds were evaluated for anti-diabetic properties in vitro using HepG2 cells. Compounds 3c, 3d, and 3i-l caused significant
Maren Vollmer et al.
Journal of agricultural and food chemistry, 66(2), 485-497 (2017-12-14)
Human colonic bacteria have an important impact on the biotransformation of flavonoid glycosides and their conversion can result in the formation of bioactive compounds. However, information about the microbial conversion of complex glycosylated flavonoids and the impact on the gut
Tsuyoshi Goto et al.
Molecular nutrition & food research, 56(3), 435-445 (2011-12-17)
Recent studies have reported that tiliroside, a glycosidic flavonoid, possesses anti-diabetic activities. In the present study, we investigated the effects of tiliroside on carbohydrate digestion and absorption in the gastrointestinal tract. This study showed that tiliroside inhibits pancreatic α-amylase (IC₅₀
Zijun Luo et al.
Colloids and surfaces. B, Biointerfaces, 92, 84-90 (2011-12-27)
The flavonoids tiliroside, rutin and naringin have been investigated as stabilizers of Pickering oil-in-water (O/W) emulsions. The mean droplet size of tetradecane emulsions was considerably smaller at higher pH, especially for rutin. The solubility of flavonoids in the aqueous phase

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